CASP - Collaborative Association Study of Psoriasis

The goal of this collaborative study is to combine the resources and expertise of three groups with long-standing studies of psoriasis genetics to identify new genetic susceptibility factors for psoriasis, a common inflammatory skin disease that affects over 4 million Americans.

We are carrying out a large genetic association study with a total of 1449 cases and 1449 controls to be examined in the first phase. DNA for each of the participants will be characterized in detail for ~500,000 genetic variants. This will allow us to identify psoriasis susceptibility alleles in previously unexplored regions of the genome.