HMS

Hybrid Motif Sampler

HMS (hybrid motif sampler) implements a novel computational algorithm specifically designed for transcription factor binding sites (TFBS) motif discovery using ChIP-Seq data. HMS combines stochastic sampling with determinstic greedy search to achieve rapid and accurate motif pattern identification. In addition, it can identify non-ignorable inter-position dependency inside TFBS motifs. The program is written in C++, and it is available for Linux, Unix, Windows, MAC OSX operating systems as a command line exeutable.

Download program

Download the latest version and the source code of HMS. [October, 2009]

Download datasets

Download ChIP-Seq and ChIP-chip datasets.

Documentation

Includes the user manual, manuscript and supplementary material describing HMS.

Update & Bug Log

Log of updates, bugs and fixes. Also has the previous versions of the program
 

Contact

For bug report, questions or comments, please contact Ming Hu (hming@umich.edu).