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UM SPH Academic Courses
Printable List of All SPH Courses with Descriptions (PDF)
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BIOSTAT449 |
| Topics In Biostatistics |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: Statistics 401 or permission of instructor |
| This course will make use of case studies to discuss problems and applications of biostatistics. Topics will include cohort and case control studies, survival analysis with applications in clinical trials, evaluation of diagnostic tests, and statistical genetics. The course will conclude with a survey of areas of current biostatistical research.
|
| This course is cross-listed with Statistics 449 in the Literature, Science and the Arts department. |
|
BIOSTAT503 |
| Introduction to Biostatistics |
|
Fall
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Staff; Mukherjee, Bhramar |
| Offered every year |
| Prerequisites: Elementary algebra |
| Fundamental statistical concepts related to the practice of public health: descriptive statistics; probability; sampling; statistical distributions; estimation; hypothesis testing; chi-square tests; simple and multiple linear regression; one-way ANOVA. Use of computer in statistical analysis. |
| Syllabus for BIOSTAT503 (PDF,
91474 bytes, last modified on Wednesday, September 03, 2008
) |
|
BIOSTAT510 |
| Statistical Computer Program Packages |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Welch, Kathy |
| Prerequisites: Biostat 503 or 553 or permission of instructor |
| Students learn use of several widely used statistical computer program packages such as BMDP, SAS and SPSS. Emphasis placed on relative merits of these packages with respect to types of statistical analyses they perform and their methods of data management. |
| Syllabus for BIOSTAT510 (PDF,
25352 bytes, last modified on Wednesday, February 01, 2006
) |
|
BIOSTAT513 |
| Application of Regression Analysis to Public Health Studies |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Sanchez, Brisa |
| Offered every year |
| Prerequisites: Biostat 503, 553 or Perm. Instr. |
| Biostat 513 will cover a general overview of linear, logistic, Poisson, and Cox regression. The course will use SPSS as the statistical software. |
|
BIOSTAT523 |
| Biostatistical Analysis for Health-Related Studies |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Schaubel, Douglas |
| Prerequisites: BIOSTAT 553; BIOSTAT 503 w/ instructors permission |
| A second course in applied biostatistical methods and data analysis. Concepts of data analysis and experimental design for health-related studies. Emphasis on categorical data analysis, multiple regression, analysis of variance and covariance. |
|
BIOSTAT553 |
| Applied Biostatistics |
|
Fall
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Kalbfleisch, Jack |
| Prerequisites: Calculus |
| Fundamental statistical concepts related to the practice of public health: descriptive statistics; probability; sampling; statistical distributions; estimation; hypothesis testing; chi-square tests; simple and multiple linear regression; one-way ANOVA. . Taught at a more advanced mathematical level than Biostat 503. Use of the computer in statistical analysis. |
| Syllabus for BIOSTAT553 (PDF,
46833 bytes, last modified on Thursday, September 04, 2008
) |
|
BIOSTAT560 |
| Statistical Methods in Epidemiology |
|
Fall
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Tsodikov, Alexander |
| Prerequisites: Biostat 523, EPID 503 or EPID 601 |
| Statistical methods commonly used in environmental epidemiology. Emphasis on choosing appropriate statistical methods and subsequent interpretation. Topics include probability, measures of association and risk, sample size calculations, SMR and PMR analysis, logical regression and survival analysis. |
| Syllabus for BIOSTAT560 (PDF,
44915 bytes, last modified on Thursday, September 04, 2008
) |
|
BIOSTAT578 |
| Practical Projects |
|
Fall, Winter, Spring, Spring-Summer, Summer
term(s) |
|
1-4 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: NONE |
| Practical projects in consultation and statistical analysis of data in research studies with health investigators. Course requirements include an approved practical work experience related to Biostatistics in consultation with a faculty advisor. May be elected more than once. Enrollment limited to Biostatistics majors with at least two full terms of prior registration. |
|
BIOSTAT600 |
| Introduction to Biostatistics |
|
Fall
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Kim, Sinae; Welch, Kathy |
| Prerequisites: Admission to a degree program in Biostatistics |
| The purpose of this course is to review basic applied statistical concepts and tools and to introduce the SPH computer network and statistical software. |
| Syllabus for BIOSTAT600 (PDF,
7198 bytes, last modified on Wednesday, February 01, 2006
) |
|
BIOSTAT601 |
| Probability and Distribution Theory |
|
Fall
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Qin, Zhaohui; Wang, Lu |
| Prerequisites: Three terms of calculus |
| Fundamental probability and distribution theory needed for statistical inference. Probability, discrete and continuous distributions, expectation, generating functions, limit theorems, transformations, sampling theory. |
| Syllabus for BIOSTAT601 (PDF,
42571 bytes, last modified on Monday, September 22, 2008
) |
|
BIOSTAT602 |
| Biostatistical Inference |
|
Winter
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Zhang, Min |
| Prerequisites: Biostat 601 |
| Fundamental theory that is the basis of inferential statistical procedures. Point and interval estimation, sufficient statistics, hypothesis testing, maximum likelihood estimates, confidence intervals, criteria for estimators, methods of constructing test and estimation procedures. |
| Syllabus for BIOSTAT602 (PDF,
49461 bytes, last modified on Wednesday, November 26, 2008
) |
|
BIOSTAT605 |
| Intro to SAS Statistical Programming |
|
Fall
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: One course in introductory statistics; Co-requisite Biostat 601 or equivalent or Perm. Instr |
| This course provides incoming master's students in biostatistics with basic experience in SAS programming for data set creation and manipulation, an introduction to SAS macros, and SAS matrix manipulation.
|
| Syllabus for BIOSTAT605 (PDF,
18613 bytes, last modified on Tuesday, January 31, 2006
) |
|
BIOSTAT610 |
| Readings in Biostatistics |
|
Fall, Winter
term(s) |
|
1-4 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: One of Biostat 503, Biostat 524, Biostat 553 or Biostat 601/Biostat 602 |
| Independent study in a special topic under the guidance of a faculty member. May be elected more than once. Enrollment is limited to biostatistics majors. |
|
BIOSTAT615 |
| Statistical Computing |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Abecasis, Goncalo |
| Prerequisites: Biostat 601 or Perm. Instr. |
| A survey of key algorithms for statistical computing and its applications in Biostatistics. The course will cover fundamental computational techniques for dynamic programming, sorting, and searching, as well statistical methods for random number generation, numerical integration, function optimization, Markov-Chain Monte Carlo, and the E-M algorithm. Enables students to understand numerical results produced by a computer and to implement their own statistical methods.
|
| Syllabus for BIOSTAT615 (PDF,
7623 bytes, last modified on Wednesday, September 10, 2008
) |
|
BIOSTAT617 |
| Theory and Methods of Sample Design (Soc 717 and Stat 580 and SurvMeth 617) |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Lepkowski, James M |
| Prerequisites: Three or more courses in statistics, and preferably a course in methods of survey sampling |
| Theory underlying sample designs and estimation procedures commonly used in survey practice. |
| This course is cross-listed with Stats 580
Soc 717
SurvMeth617 in the Rackham
department. |
| Syllabus for BIOSTAT617 (PDF,
48195 bytes, last modified on Monday, September 08, 2008
) |
|
BIOSTAT619 |
| Clinical Trials |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Braun, Thomas |
| Prerequisites: Biostatistics 601 or equivalent or Perm. Instr. One course Introductory Statistics |
| This course is designed for individuals with a strong quantitative background that are interested in the scientific, policy, design and management aspects of clinical trials. Topics include types of clinical research, bias and random error, study design, ethics, treatment allocation, randomization and stratification quality control, power and sample size, group sequential monitoring, crossover designs and meta-analysis. |
| Syllabus for BIOSTAT619 (PDF,
73937 bytes, last modified on Thursday, September 04, 2008
) |
|
BIOSTAT630 |
| Statistical Methods in Biological Assay |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 650 and Co-requisite Biostat 651 or Perm. Instr. |
| Logic of biological assay; dosage response curves; quantitative and quantal responses; parallel line and slope-ratio assays; simplified estimators; sequential assays; problem of design. |
|
BIOSTAT642 |
| Introduction to Functional MRI |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| This course presents the basic skills to design and analyze functional magnetic resonance imaging (fMRI) experiments. We start by reviewing the basic Matlab and Unix skills necessary to manipulate image data. Next we introduce the principles of MRI and the nature of the Blood Oxygenation Level Dependent (BOLD) effect, including artifacts that corrupt the BOLD signal. We cover blocked and event-related designs, and how to optimize statistical power of design. We cover subject safety. |
| Syllabus for BIOSTAT642 (PDF,
13970 bytes, last modified on Wednesday, February 01, 2006
) |
|
BIOSTAT645 |
| Time Series Analysis with Biomedical Applications |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 602, Biostat 650 or Perm. Instr |
| Introduction to statistical time series analysis with an emphasis on frequency domain (spectral) methods and their applications to biomedical problems. Topics include autocorrelation, stationarity, autoregressive and moving average processes, power spectra, periodgrams, spectral estimation, linear filters, complex demodulation, autoregressive integrated moving average (ARIMA) models, cross-correlation, cross-spectra, coherence, time and frequency domain linear regression. The methods will be illustrated in applications to various areas of public health and medical research such as environmental health, electrophysiology, and endocrinology. |
|
BIOSTAT646 |
| Data Analysis in Molecular Biology |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Qin, Zhaohui |
| Prerequisites: Graduate Standing and Statistics 400,Biostatistics 523, or Biostatistics 553 or permission of instructor |
| The course will cover statistical methods used to analyze data in experimental molecular biology. The course will primarily cover topics relating to gene expression data analysis, but other types of data such as genome sequence data that is sometimes analyzed in concert with expression data will also be covered. |
| This course is cross-listed with Statistics 545 (Home Program)
Bioinformatics in the Rackham department. |
|
BIOSTAT650 |
| Applied Statistics I: Linear Regression |
|
Fall
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Kim, Sinae |
| Prerequisites: BIOSTAT601 |
| Graphical methods, simple and multiple linear regression; simple, partial and multiple correlation; estimation; hypothesis testing, model building and diagnosis; introduction to nonparametric regression; introduction to smoothing methods (e.g., lowess) The course will include applications to real data. |
| Syllabus for BIOSTAT650 (PDF,
34066 bytes, last modified on Thursday, September 04, 2008
) |
|
BIOSTAT651 |
| Applied Statistics II: Extensions for Linear Regression |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Kim, Sinae |
| Prerequisites: BIOSTAT601 and BIOSTAT650 |
| Introduction to maximum likelihood estimation; exponential family; proportion, count and rate data; generalized linear models; link function; logistic and Poisson regression; estimation; inference; deviance; diagnosis. The course will include application to real data. |
| Syllabus for BIOSTAT651 (PDF,
15241 bytes, last modified on Tuesday, January 31, 2006
) |
|
BIOSTAT652 |
| Design of Experiments |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 651 |
| Planning of experiments, use of contrasts in analysis of complete and incomplete block designs. A unified approach to analysis of designs through use of eigen-values and eigenvectors of the association matrix. A-D-E optimality criteria factorial exponents; efficiency of a design, confounding, fractional replication, response-surface designs, rotability criterion, mixture designs, analysis of two-way designs, analysis when blocks are random, applications in biological and biomedical problems. |
| Syllabus for BIOSTAT652 (PDF,
59318 bytes, last modified on Tuesday, January 31, 2006
) |
|
BIOSTAT653 |
| Applied Statistics III: ANOVA and Linear Mixed Models |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Banerjee, Mousumi |
| Prerequisites: BIOSTAT650 and concurrent enrollment in BIOSTAT651 |
| One-way layout, two-way and higher-way layouts; fixed effects and random effects; multiple comparisons; matching and blocking; balanced and unbalanced designs; weighted least squares; repeated measures; longitudinal and clustered data; linear mixed models; variance components; BLUP; REML. The course will include applications to real data. |
|
BIOSTAT664 |
| Special Topics in Biostastics |
|
Winter
term(s) |
|
1-4 Credit Hour(s)
|
| Instructor(s):
Zoellner, Sebastian; Tsodikov, Alexander; Rosenberg, Noah |
| Prerequisites: Permission of instructor |
| Master's level seminar designed to provide an extensive review of a number of substantive and methods and skill areas in biostatistics. Readings, discussion, and assignments are organized around issues of mutual interest to faculty and students. Reviews and reports on topics required in the areas selected. May be elected more than once. |
|
BIOSTAT665 |
| Statistical Population Genetics |
|
Fall, Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Rosenberg, Noah; Zoellner, Sebastian |
| The first half of the course concentrates on classical population genetics. We introduce topics such as Hardy-Weinberg equilibrium, models of selection for populations of infinite size and population subdivision.
The second half of the course focuses on coalescent theory, covering migration, changes in population size and recombination. We provide guidelines how these models can be used in to infer population genetic parameters. Finally, some recent results and methods from the population genetic literature are discussed. |
| This course is cross-listed with Bioinformatics 665, Human Genetics 665 in the Bioinformatics Graduate Program department. |
|
BIOSTAT666 |
| Statistical Models and Numerical Methods in Human Genetics |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Boehnke, Michael L |
| Prerequisites: Biostat 602 or Perm. Instr. |
| Introduction to current statistical methods used in human genetics. Topics will include sampling designs in human genetics, gene frequency estimation, the coalescent method for simulation of DNA sequences, linkage analysis, tests of association, detection of errors in genetic data, and the multi-factorial model. The course will include a simple overview of genetic data and terminology and will proceed with a review of numerical techniques frequently employed in human genetics.
|
| Syllabus for BIOSTAT666 (PDF,
7573 bytes, last modified on Wednesday, February 01, 2006
) |
|
BIOSTAT675 |
| Survival Time Analysis |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Murray, Susan |
| Prerequisites: Biostat 602 and Biostat 650 |
| Concepts and methods for analyzing survival time data obtained from following individuals until occurrence of an event or their loss to follow-up. Survival time models, clinical life tables, survival distributions, mathematical and graphical methods for evaluating goodness of fit, comparison of treatment groups, regression models, proportional hazards models, censoring mechanisms. |
| Syllabus for BIOSTAT675 (PDF,
54105 bytes, last modified on Thursday, September 04, 2008
) |
|
BIOSTAT680 |
| Applications of Stochastic Processes I |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 601 and Math 450 or equiv |
| Conditional distributions, probability generating functions, convolutions, discrete and continuous parameter, Markov chains, medical and health related applications. |
| Syllabus for BIOSTAT680 (PDF,
56428 bytes, last modified on Wednesday, February 01, 2006
) |
|
BIOSTAT682 |
| Applied Bayesian Inference |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Johnson, Timothy |
| Prerequisites: Biostat 602, Biostat 650 and Biostat 651 |
| Introduction to Bayesian Inference. Bayesian large sample inference, relationship with maximum likelihood. Choice of model, including prior distribution. Bayesian approaches to regression generalized linear models, categorical data, and hierarchical models. Empirical Bayes methods. Comparison with frequentist methods. Bayesian computational methods. Assessment of sensitivity to model assumptions. Emphasis on biomedical applications. |
| Syllabus for BIOSTAT682 (PDF,
12546 bytes, last modified on Monday, February 06, 2006
) |
|
BIOSTAT685 |
| Elements of Nonparametric Statistics |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 602 or STAT 511, and Biostat 650 or Perm. Instr |
| First half covers theory and applications of rank and randomization tests: sampling and randomization models, randomization t-test, Wilcoxon rank sum and signed rank tests, Kruskal-Wallis test, asymptotic result under randomization, relative efficiency; second half covers theory and applications of nonparametric regression: smoothing methods, including kernel estimators, local linear regression, smoothing splines, and regression splines, methods for choosing the smoothing parameter, including unbiased risk estimation and cross-validation, introduction to additive models. |
| Syllabus for BIOSTAT685 (PDF,
68383 bytes, last modified on Tuesday, January 31, 2006
) |
|
BIOSTAT690 |
| Health Applications of Multivariate Analysis |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 650 and Biostat 651 and Math 417 or Perm. Instr. |
| Techniques of multivariate analysis related to health and biomedical problems. Emphasis on computational techniques and programs with health examples. Tests of significance for one, two or more populations; general linear model; multivariate analyses of variances and covariances; correlation procedures; principal components and discriminant analyses. |
| Syllabus for BIOSTAT690 (PDF,
14721 bytes, last modified on Tuesday, January 31, 2006
) |
|
BIOSTAT695 |
| Analysis of Categorical Data |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Song, Peter Xuekun |
| Prerequisites: Biostat 602 and Biostat 660 |
| Regression models for the analysis of categorical data: logistic, probit and complementary log-log models for binomial random variables; log-linear models for cross-classifications of counts; regression models for Poisson rates; and multinomial response models for both nominal and ordinal responses. Model specification and interpretation are emphasized, and model criticism, model selection, and statistical inference are cast within the framework of likelihood based inference. |
| Syllabus for BIOSTAT695 (PDF,
29132 bytes, last modified on Wednesday, September 03, 2008
) |
|
BIOSTAT699 |
| Analysis of Biostatistical Investigations |
|
Winter
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Taylor, Jeremy; Elliot, Michael |
| Prerequisites: Registration for last term of studies to complete MS or MPH |
| Identifying and solving design and data analysis problems using a wide range of biostatistical methods. Written and oral reports on intermediate and final results of case studies required. |
|
BIOSTAT800 |
| Seminar in Biostatistics |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Staff |
| Presentations and discussions of current consulting and research problems. May be elected more than once. Enrollment limited to biostatistics majors. |
|
BIOSTAT803 |
| Biostatistics in Cancer Seminar |
|
Fall, Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Taylor, Jeremy |
| Prerequisites: Perm. Instr. |
| The purpose of this class is to describe biostatistical research that is occuring in collaboration with cancer researchers, and to provide exposure to the field of cancer research. Activities inlcude seminars on statistical methods in cancer; presentations of cancer research; presentations of articles from statistical literature; discussion of cancer clinical tiral protocals and grant proposals; and visits to research laboratories. Students formally in the training program are expected to enroll in this course every semester. The course is open to students not participating in the training grant. It is open to both PhD and Masters students. |
|
BIOSTAT815 |
| Advanced Topics in Computational Statistics |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Abecasis, Goncalo |
| Prerequisites: Biostat 601, Biostat 602 and Biostat 625 or equiv and proficiency in Fortran or C |
| Modern numerical analysis for statisticians. Combination of theory and practical computational examples illustrating the current trends in numerical analysis relevant to probability and statistics. Topics choose from numerical linear algebra, optimization theory, quadrature methods, splines, and Markov chains. Emphasis on newer techniques such as quasi-random methods of integration, the EM algorithm and its variants, and hidden Markov chains. Applications as time permits to areas such as genetic and medical imaging. |
| Syllabus for BIOSTAT815 (PDF,
7623 bytes, last modified on Tuesday, January 31, 2006
) |
|
BIOSTAT820 |
| Readings in Biostatistics |
|
Fall, Winter, Spring-Summer
term(s) |
|
1-4 Credit Hour(s)
|
| Instructor(s):
Staff |
| Students assigned special topics for literature study under guidance of individual faculty members. May be elected more than once. Enrollment limited to biostatistics majors. |
|
BIOSTAT830 |
| Advanced Topics in Biostatistics |
|
Fall
term(s) |
|
1-4 Credit Hour(s)
|
| Instructor(s):
Nan, Bin |
| Advanced training in biostatistical methods primarily for doctoral students. Format will include lectures, readings, presentations and discussions in an area of special interest to students and faculty, such as stopping rules and interim analysis in clinical trials, conditional and unconditional inference and ancillarity, or nonparametric regression. |
| Syllabus for BIOSTAT830 (PDF,
48287 bytes, last modified on Thursday, September 04, 2008
) |
|
BIOSTAT840 |
| Advanced Topics in Data Analysis |
|
Fall, Winter, Spring-Summer
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 650 and Biostat 651 |
| Alternate methods of data analysis useful when data do not fulfill unusual assumptions of statistical tests. Using articles from the literature, students learn methods of data analysis more robust than usual methods and how to choose among them. Focuses on comparison of groups, ANOVA and regression. |
|
BIOSTAT845 |
| Advanced Topics in Times Series Analysis |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 645, Stat 531 or Perm. Instr. |
| Advanced theory of stationary univariate and multivariate time series. Additional advanced topics such as analysis of non-stationary, non-linear, and/or categorical time series; time-frequency analysis; and statistical methods based on the wavelet transform or related transforms. Application of methods to time series data sets from health research. |
|
BIOSTAT850 |
| Research in Biostatistics |
|
Winter, Spring-Summer
term(s) |
|
2-4 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Research on selected topics involving the application of statistical methods to health problems. May be elected more than once. Enrollment limited to biostatistics majors. |
|
BIOSTAT851 |
| Linear Statistical Models (Stat 642) |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 602 and Biostat 651 or Perm. Instr. |
| Theory of multivariate normal distribution, distribution of quadratic forms, Cochran's theorem, Gauss-Markov theorem, general linear hypothesis, experimental design models, Wishart distribution. |
|
BIOSTAT855 |
| Regression Models in Complex Sample Design Settings (JPSM/MPSM 895) |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Elliot, Michael |
| Prerequisites: BIOSTAT617, BIOSTAT650, BIOSTAT651, or instructor permission |
| This course examines a range of statistical regression analysis techniques for modeling survey data, and presents methods to compensate for design features for complex sample survey data. Course topics include likelihood estimation and testing; application of likelihood methods to linear and generalized linear models, including logistic, probit, generalized (multinomial) logit, Poisson, and negative binomial models; time-to-event (survival analysis) models; regression models for longitudinal data; and propensity score and Bayesian regression modeling. |
| This course is cross-listed with MPSM 895 in the Michigan Program for Survey Methodology/Institute for Social Research department. |
| Syllabus for BIOSTAT855 (PDF,
36599 bytes, last modified on Thursday, September 04, 2008
) |
|
BIOSTAT866 |
| Advanced Topics in Genetic Modeling |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Zoellner, Sebastian |
| Not offered 2008-2009 |
| Prerequisites: Biostat 601, Biostat 602, Biostat 666 or Perm. Instr. |
| Advanced topics in quantitative genetics with emphasis on models for gene mapping, pedigree analysis, reconstruction of evolutionary trees, and molecular genetics experiments, computational mathematics, and statistical techniques such as Chen-Stein Poisson approximations, hidden Markov chains, and the EM algorithm introduced as needed. |
|
BIOSTAT870 |
| Analysis of Repeated Measurements |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Raghunathan, Trivellore |
| Not offered 2008-2009 |
| Prerequisites: Math 417, Biostat 602, Biostat 651 and one of Biostat 690, Biostat 851, or Biostat 890 |
| Mixed model analysis of variance; multivariate profile analysis; linear mixed effects models with unbalanced designs, time-varying covariates, and structured covariance matrices; maximum likelihood (ML), restricted maximum likelihood (REML), and Bayes estimation and inference; nonlinear mixed effects models. |
|
BIOSTAT875 |
| Advanced Topics in Survival Analysis |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Schaubel, Douglas |
| Not offered 2008-2009 |
| Prerequisites: Biostat 675 |
| Lectures and readings from the literature on advanced topics in survival analysis. Covers regression for censored data, general event-history data and models, competing risks. Statistical, mathematical, and probabilistic tools used in survival analysis are extended for these general problems. |
|
BIOSTAT880 |
| Statistical Analysis With Missing Data |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Little, Roderick |
| Not offered 2008-2009 |
| Prerequisites: Biostat 602 and 651, and at least one of Biostat 690, Biostat 851, Biostat 890, or Biostat 895 or Perm Inst. |
| Statistical analysis of data sets with missing values. Pros and cons of standard methods such as complete-case analysis, imputation. Likelihood-based inference for common statistical problems, including regression, repeated-measures analysis, and contingency table analysis. Stochastic censoring models for nonrandom nonresponse. Computational tools include the EM algorithm, the Gibbsﾒ sampler, and multiple imputation. |
|
BIOSTAT885 |
| Nonparametric Statistics |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Song, Peter Xuekun |
| Prerequisites: Biostat 601/602 or Perm. Instr. |
| Theory and techniques of nonparametrics and robustness. M-estimation, influence function, bootstrap, jackknife, generalized additive models, smoothing techniques, penalty functions, projection pursuit, CART. |
|
BIOSTAT890 |
| Multivariate Statistical Models (Stat 640) |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Math 417 and either Stat 511 or Biostat 602 and Perm. Instr. |
| Derivation of multivariate techniques: multivariate estimation, T, criteria for testing linear hypothesis, test for additional information, testing covariance matrices, factor analysis, growth curves and elementary time series. |
| Syllabus for BIOSTAT890 (PDF,
70844 bytes, last modified on Tuesday, January 31, 2006
) |
|
BIOSTAT895 |
| Analysis of Multivariate Categorical Data |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biostat 651 and Biostat 695 or Perm. Instr. |
| Probability models for two-way tables; multi-factor, multi-response framework; product multinomial distribution theory; Taylor series estimates of variance, weighted least squares and Wald statistics; constraint equations; models for characterizing interactions; step-wise variable selection; factorial designs with multinomial responses; repeated measurement experiments; log-linear models; paired-choice and bioassay experiments; life-table models. |
|
BIOSTAT990 |
| Dissertation/Pre-Candidacy |
|
Fall, Winter, Spring-Summer
term(s) |
|
1-8 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: (1-8 Full term, 1-4 Half term) |
| Election for dissertation work by doctoral student not yet admitted to status as a candidate. |
|
BIOSTAT995 |
| Dissertation Research for Doctorate in Philosophy |
|
Fall, Winter, Spring-Summer
term(s) |
|
1-8 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: Admission to Doctoral Program(1-8 Full term, 1-4 Half term) |
| Election for dissertation work by doctoral student who has been admitted to status as a candidate. |
|
EHS311 |
| Naturally Occuring Biological Toxins |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biology, Chemistry (organic preferred) |
| Explanation of principles needed to understand sources, adverse effects, mechanism of action, and treatment for exposure to naturally occurring toxins from substances such as mushrooms, herbs, plants, microbes, marine organisms, and insect and animal venom. Implications of bioterrorism will be discussed. |
| This course is cross-listed with Naturally Occurring Biological Toxins, EHS 311 in the LS&A department. |
|
EHS500 |
| Principles of Environmental Health Sciences |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Hu, Howard |
| Prerequisites: Seniors with Perm. Instr. |
| This course provides a broad overview of some of the most important and current challenges to human health from environmental and occupational risk factors while teaching the basic knowledge and multi-disciplinary skills used to assess, control, and prevent them. We will address specific threats, such as outdoor and indoor air pollution, toxic metals, pesticides, radiation and occupational stressors; analyze impacts on specific diseases and injuries, such as cardiovascular disease, asthma, cancer, musculoskeletal injuries and impaired child development;; and introduce emerging threats, such as the hormone-mimicing potential of plastic chemicals and the impact of global climate change on heat-related mortality and shifting patterns of infectious disease. Emphasis will also be given to understanding the worsening environmental health impacts of industrialization on developing countries, the effects of globalization, such as the growing movement of hazardous industries, products, and wastes across borders. and the rise of the environmental justice movement. The course fulfills the MPH core competency in environmental health and is also open to students in LSA and other UM graduate schools. A basic understanding (high school level) of human biology and chemistry is recommended. |
|
EHS501 |
| Occupational Environmental Disease |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
O'Neill, Marie |
| Prerequisites: EHS 505, 506 or equivalent |
| Selected topics in the diagnosis, treatment and prevention of environmental and occupational disease, including coverage of toxins, exposures, organ systems, and disease. Lectures and case studies address exposures to solvents, radon, lead and other metals, asbestos and other pneumoconiotic dusts, outdoor air pollution, indoor air quality, and noise. Major health effects and disease categories covered include cancer, respiratory disease, and reproductive health. Prerequisites: basic knowledge of human physiology, and exposure assessment. (These requirements may be taken concurrently with this course). |
|
EHS502 |
| Environmental Health in Developing Areas |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Nriagu, Jerome |
| Not offered 2008-2009 |
| The course provides a review of basic environmental health knowledge and skills and their applications in developing areas of the world; case studies from Africa, South America, and Southeast Asia. Delivery will include lectures, reading assignments individual exercises, and term paper. |
|
EHS503 |
| Law and Policy in Environmental Health |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| This course is intended to familiarize students with the laws governing the administrative process by which science is translated into science policy by government in the form of regulations in the areas of environmental health, occupational health and toxicology. The course also illustrates the process by which costs are compared to benefits in choosing the final science policy. Case studies in the form of appellate and Supreme Court opinions are used to illustrate risk-cost-benefit evaluation, the law'ﾒs use of science, and other topics in law and policy. Syllabus cases illustrate environmental health policy in the areas of hazardous chemicals, clean air, clean water, drinking water, radioactive waste, occupational health, new drug approval, and food additives. The course is also intended to demonstrate how judges analyze issues in areas involving scientific information, that is, to illustrate legal reasoning. |
|
EHS504 |
| Genes and the Environment |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Franzblau, Alfred |
| Prerequisites: None. |
| In past years disease causation frequently was thought of as a "dichotomy" between genes ("nature") and the environment ("nurture"). More recently this view has been replaced with a more holistic perspective that emphasizes the importance of interactions between genes and environmental and/or occupational exposures. The focus of this course will be on interaction between genes and specific environmental and/or occupational exposures. The course will consist of detailed evaluation of specific examples of gene-exposure interaction (e.g., beryllium-related lung disease, peripheral neurotoxicity from organophosphate pesticides, bladder cancer and amine exposure) the underlying science of such examples, medical consequences, potential policy and social implications of current and future scientific knowledge, and review of current and pending legislation that address these issues. The course will meet for one two-hour session per week, and will be conducted in an advanced seminar-style format. Student will be expected to make presentations and lead discussion, in addition to presentations by faculty and outside guests. Student evaluations will be based on written reports, class participation and class presentation. |
|
EHS506 |
| Principles of Toxicology |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Loch Caruso, Rita |
| Prerequisites: Biology, Organic Chemistry, Grad Standing or Perm. Instr. |
| Principles underlying the chemical, physiological and anatomical basis of toxicity. Dose-response relationships, toxicokinetics, and biotransformation, mechanisms of cellular injury and death, organ system toxicity, developmental toxicology, genotoxicity and toxicogenomics, and chemical carcinogenesis. Principles will be illustrated where appropriate with specific examples of toxicity from environmental contaminants and pharmaceutical agents. |
|
EHS507 |
| Principles of Exposure Assessment |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Robins, Thomas |
| Prerequisites: BIOS 503, EPID 503, EPID 601, EHS 505 (concurrent enrollment is acceptable) or Perm. Instr. |
| This course is designed to provide the knowledge and skills necessary to assess exposure to environmental agents. Topics include the selection of study populations; the conditions under which people or other target species could be exposed; identification and quantification of exposure pathways; the design of exposure assessment strategies; integration of exposure and population information; and the evaluation of historical (exposure reconstruction), current and prospective exposures. The course focuses on occupational and environmental settings and includes chemical, biological (bacteria, fungi, pathogen) and physical agents that may be air-, water-, food- or vector-borne. |
|
EHS508 |
| Principles of Risk Assessment |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Jolliet, Olivier |
| Prerequisites: EHS 507, Epidemiology (concurrent enrollment acceptable) or Perm. Instr. |
| This course is designed to provide the knowledge and skills necessary to understand risk assessment methods. Students will understand the use and limitations of risk assessment in establishing exposure standards, acceptable concentrations, and the environmental criteria for hazardous substances that present a risk of carcinogenic or other health effects and the suitability of risk assessment for such purposes. The basic approaches to environmental risk assessment will be emphasized, including methods for identifying health effects, modeling of health effects, and derivation of risk estimates. Methods for dealing with uncertainties as well as limitations and criticisms of risk assessment methods will be discussed. Specific examples of risk assessments will be analyzed and critiqued. |
|
EHS509 |
| Ecological Toxicology |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Basu, Niladri |
| Prerequisites: University level biology and chemistry |
| 'Ecological Toxicology' is a graduate-level course designed to provide an understanding of how ecological receptors (e.g., fish, mammalian wildlife, birds) are exposed to contaminants and how these organisms toxicologically respond at multiple tiers of biological organization, from cells to individuals to ecosystems. Fundamental concepts in ecological toxicology (source, fate, transport, and toxicity of contaminants) will be covered from both a theoretical and applied perspective. These fundamental concepts will be reinforced by case studies that draw upon historical examples, contemporary topics, and the peer-reviewed scientific literature. The processes by which pollutants are tested, evaluated, regulated, and monitored to ensure ecological health will be critically examined. Humans are an integral component of the ecosystem, and this course will critically explore how ecological toxicology can be used to advance human health. |
|
EHS513 |
| Pathologic Basis of Disease |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Philbert, Martin |
| This course will examine the major pathological processes of humans and mammals elicited by chemical, biological and physical entities of interest to practitioners of Public Health. Specifically, the pathophysiological mechanisms of disease will be examined with a view to understanding the cellular, biochemical and molecular processes that cover injury, degeneration and regeneration. |
|
EHS515 |
| Naturally Occurring Biological Toxins |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biology, Chemistry (organic preferred) |
| Explanation of principles needed to understand sources, adverse effects, mechanism of action, and treatment for exposure to naturally occurring toxins from substances such as mushrooms, herbs, plants, microbes, marine organisms, and insect and animal venom. Implications of bioterrorism will be discussed |
| This course is cross-listed with Naturally Occurring Biological Toxins, EHS 311 in the LS&A department. |
|
EHS530 |
| Nutrition in Public Health |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Principles of normal nutrition and relation of nutrition to health. Designed for graduate students in other programs and schools, especially students in health education, physical education and nursing. |
|
EHS531 |
| Herbs and Dietary Supplements |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biology |
| The course will examine the status of the usage, production, claimed effects, mechanism of effects and potential misuse and safety of the major herbs and dietary supplements in the US. The course will carefully review the literature and examine the evidence that support the claimed or alleged effects. The course will also discuss the government and industry rules and regulations and the controversies associated with the use of these products. |
|
EHS540 |
| Maternal and Child Nutrition |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Cole, Suzanne |
| Explores the nutritional requirements and support associated with the physiologic changes of pregnancy, lactation, and fetal, infant, child and adolescent growth. Review of recent nutrition issues and recommendations related to mothers and children. |
|
EHS547 |
| Food Science |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Organic Chemistry |
| An examination of food composition and the chemical and physical changes that result from food processing. Discussion of foods as complex systems containing a wide variety of chemicals including nutrients, phytochemicals, functional ingredients, natural or transferred toxins and additives. Discussion of changes in chemicals with different types of food preservation. Consideration of health risks associated with dietary exposure to selected nutrients and other chemicals. Exploration of the role of sensory analysis related to food acceptance. Overview of important regulations related to the content of food products. |
|
EHS550 |
| Introduction to Occupational and Environmental Health |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Vincent, James |
| Prerequisites: Grad Status or Senior Standing |
| Discussion of the basic concepts of occupational and environmental hygiene; recognition and evaluation of chemical,physical and biological hazards; the human environment; control hierarchies, strategies and technologies; personal protection; criteria and standards; the international dimension; and ethical issues. The course provides basic underpinnings of the nature of theory and practice in occupational and environmental hygiene, and thus provides a structural framework for thinking about the field, identifying linkages between disciplines and specialties, and providing a platform for more advanced study in the individual areas listed. The course is offered as a three-credit
course in both the regular term and in the OJ/OC format.
|
|
EHS556 |
| Occupational Ergonomics |
|
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Principles, concepts and procedures concerned with worker performance, health and safety. Topics include: biomechanics, job safety, anthropometry, work physiology, psychophysics, work stations, tools, work procedures, work standards, Musculoskeletal disorders, noise, vibration, heat stress and the analysis and design of work. |
|
EHS570 |
| Water Quality Management |
|
Fall, Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Xi, Chuanwu |
| Principles of science and engineering used in the evaluation and control of water quality. Includes current legislation, types of pollution, sources and nature of pollution, introduction to water quality management practices, water supply and treatment, hydrologic concepts, effects of waste discharge on receiving waters, lake management, and water quality criteria and standards. |
|
EHS571 |
| Water Quality Management Practices |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: EHS 570 |
| Principles and methods in water quality management. Methods, applications, and water quality considerations associated with water reclamation and re-use; soils and sediments as factors in water pollution control; flow regulation for water quality management; economics and institutions in water quality management. |
|
EHS572 |
| Environmental Impact Assessment (NRE 514) |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Batterman, Stuart |
| Prerequisites: EHS 574, Grad Status |
| A comprehensive framework for predicting and evaluating environmental impacts is presented. The course emphasizes the theory, application, integration and evaluation of models simulating transport and fate of contaminants in air, surface and ground water, and soil. Case studies and computer exercises demonstrate contemporary exposure and health risk assessment problems. |
| This course is cross-listed with NRE514 in the NRE department. |
|
EHS574 |
| Environmental Chemistry |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Nriagu, Jerome |
| Prerequisites: College Chemistry including Organic Chemistry and Calculus |
| Environmental chemistry of the atmosphere, hydrosphere, geosphere and soils. Review of physical and chemical hazards and sources, distribution, transformations, routes to man of environmental contaminants. Human exposure assessment procedures and applications in health risk analysis programs. |
|
EHS575 |
| Population-Environmental Dynamics (SNRE 545) |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| This course examines the dynamics of the relationship between human populations and the global environment with a focus upon critical time periods in the evolution of societies. Population-environment dynamics are visualized as a family of transitions occurring across many sectors of society. Transitions examined include forestry, agriculture, demography, epidemiology, toxicity (air and water pollution, solid waste), urbanization, energy, transportation, and education. |
|
EHS576 |
| Microbiology in Environmental Health |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Xi, Chuanwu |
| Prerequisites: Biology, Grad Standing or Perm. Instr. |
| GGraduate level course on basic knowledge about microbes in the environment and its impact on public health. Topics will include:
- introduction on microbiology; - growth and control of microbes in the environment;
- characterization and identification of microbes in the environment;
- biofilms and its control;
- transmission and persistence of health-related microbes in various environments such as water, air, food, indoor and industrial settings;
- microbial transformation of organic and metal contaminants in the environments;
- spread of antibiotic resistance in the environment. |
|
EHS578 |
| Practical Projects |
|
Fall, Winter, Spring, Spring-Summer, Summer
term(s) |
|
1-4 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: None |
| Practical Projects in the application of theory and principles of Environmental Health Sciences in public health settings. Course requirements include an approved practical work experience related to Environmental Health Sciences in consultation with a faculty advisor. May be elected more than once. Enrollment limited to Environmental Health Sciences majors with at least two full terms of prior registration. |
|
EHS579 |
| Environmental Risk Communication (SNRE 551) |
|
Fall
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Graduate Standing or Perm. Instr. |
| This course provides a brief introduction to environmental risk assessment and management and then focuses on environmental risk communication. With the help of case studies, students evaluate existing risk communication practices and formulate ways to change these practices such that they will lead to improved environmental risk decisions. |
|
EHS580 |
| Conservation of Biological Diversity (SNRE 517) |
|
Fall
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: General Ecology (Bio 381), Grad Status or Perm. Instr. |
| Overview of historic and present-day causes of species extinction, and of biological principles central to species conservation and sustainable management of ecosystems. |
|
EHS581 |
| Principles of Radiological Health |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Miklos, Joseph |
| Not offered 2008-2009 |
| Prerequisites: Calculus |
| Broad principles and practices of radiological health for environmental and occupational health generalists. Basic physics, measurement, control of radiation sources and bioeffects, risks, and control policies. Lectures and demonstrations. |
|
EHS582 |
| Principles of Community Air Pollution |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Keeler, Gerald |
| Discussion of economic, nuisance, and health aspects, emphasizing sources, causes, effects, control measures, and the organization and administration of community control programs. |
|
EHS583 |
| Radiation Biology |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Ljungman, Mats |
| Prerequisites: Biology |
| Integration of current knowledge about radiation effects processes on mammals, with particular emphasis on mechanisms of radiogenic cancer. Quantitative evaluation of relations between characteristics of various radiation exposures and somatic and genetic effects in humans. Radiation protection and therapeutic measures. Lectures and a student research paper. |
|
EHS585 |
| Food Safety Management |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Grad status |
| Evaluation of Food safety from multiple perspectives, including microbial and chemical (pesticide residues, food packaging materials, inorganic/organic materials) contamination. Identification of methods for estimating exposure to chemicals carried by food. Identification of food services systems and methods for quality control/changing the risks for food contamination. Utilization of HACCP (Hazardous Analysis Critical Control Point) in different food service situations. Provision of managerial level training course for inspection/monitoring of food establishments. |
|
EHS586 |
| Introductory Seminar in Environmental Health Sciences |
|
Fall
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Grad Standing |
| An overview of research and practice in the field of environmental health sciences. This weekly seminar is designed to introduce entering students to EHS faculty, to highlight topical issues, and to provide a common forum for EHS students. EHS faculty will introduce their specialty areas and present short seminars on their research. Approximately once per month (coinciding with OJ/OC weekends), outside speakers will present seminars addressing crosscutting issues in the environmental health sciences. The seminar is required for all first-year students. |
|
EHS588 |
| Environmental Law (SNRE 475) |
|
Fall, Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Introduces students to Environmental Law and the impact of the legal process on decisions that affect the environment. Topics include common law tort actions, toxic tort actions, statutory controls of pollution and other environmentally harmful activities. Additional areas include administrative agency structure and performance, Constitutional rights to environmental quality and more. |
|
EHS591 |
| Equity Issues in Environmental Health |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Nriagu, Jerome |
| Not offered 2008-2009 |
| Prerequisites: Grad Status |
| The course will examine equity issues in environmental health research and practice. Emphasis will be on the sources of inequity (specific environmental hazards), and documentation of environmental injustice using different spatial scales and time frames. It will provide a commentary on the desirability for affected communities to have meaningful input into the design and implementation of environmental health assessment, as well as in the use and communication of the results. |
|
EHS600 |
| Professional Perspectives in Environmental Health |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Jolliet, Olivier |
| Prerequisites: Grad Status, Completion of approved internship, research or practical experience |
| This project-oriented course provides the student the opportunity to integrate academic principles, practical skills and concepts in environmental health as related to the broader scope of public health. Students will carry out a 2 credit hour applied group project, having to synthesize their acquired knowledge from different courses and subplans to address real world problems. Students will provide oral presentation (intermediary and final) and written reports on the conducted project. This culminating capstone course will be elected during the professional students last fall term in residence. |
| Syllabus for EHS600 (PDF,
56437 bytes, last modified on Tuesday, October 21, 2008
) |
|
EHS608 |
| Environmental Epidemiology |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
O'Neill, Marie |
| Prerequisites: Epid600, Biostat 553 or 503, EHS 506 and 507, 550 |
| This course will serve as an introduction to topics in environmental epidemiology, covering major areas of current inquiry in this field. It will convey the basic tools required to critically read the literature and to develop appropriate study designs in light of intended applications. The class meeting will include lectures and student-led discussions. This course will review epidemiologic methods used in evaluating the health effects of physical, biological and chemical agents in the environment and the available evidence on the health effects of such exposures. We will also consider policy and public health applications of the scientific evidence. Topics include lectures on methodology and major environmental exposures, discussions based on review and critiques of current literature, and presentations by outside experts on specific environmental epidemiology issues of current interest. After taking this course, students should have a better understanding of the scope, limitations, applications and future of environmental epidemiology. |
| This course is cross-listed with EPID608 in the Epidemiology department. |
|
EHS612 |
| Biochemical and Molecular Toxicology |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Harris, Craig |
| Prerequisites: Biol Chem 515 or equivalent, EHS 511 |
| The objective of this course is to provide an in-depth analysis of the biochemical and molecular pathways altered in cells and organisms through exposure to environmental and therapeutic chemicals. The content is directed toward the needs of doctoral and masters students in the basic biomedical sciences involved in laboratory research projects. Topics will cover areas of modern research emphasis and focus on how chemicals act to disturb cellular processes through interaction with cellular receptors, ion channels, transporters, signal transduction pathways, transcription factors, metabolic pathways, enzymes, cytoskeletal elements and other macromolecular targets. Specific information about the latest theories on the regulation and initiation of cell death, mediation of toxicity through hredox status and oxidative stress, mechanisms of carcinogenesis, genoxicity and immunotoxicology will also be discussed. |
|
EHS616 |
| Introduction to Toxicological Pathology |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Philbert, Martin |
| Prerequisites: Physiology and EHS 511 or equivalent. |
| This course will provide and introduction to the histologic damage produced by chemical toxicants. A combination of lectures, student-led discussions and slide-reading sessions will be used to integrate concepts of toxicological mechanism, physiology and pathologic outcome. Emphasis will be place on molecular methods and mechanisms used for the diagnosis and investigative toxicological pathology. The pathology associated with chemicals that damage the major organ systems of humans and mammals will be discussed. During the two credit hours of didactic class presentations student will lead discussions on the pathologic effects of chemicals on cells, tissues and organs and the pathophysiologic outcome. This course is intended for advanced graduate students in the life sciences. |
|
EHS620 |
| Mechanisms of Endocrine Toxicology and Hormone Metabolism |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Grad Status, Biochemistry, Physiology |
| Analysis and integration of scientific information to enhance understanding of molecular and cellular mechanisms of endocrine toxicity. Emphasis is on student discussion of theoretical and practical aspects of mechanistic studies based on assigned reading from the scientific literature. |
|
EHS621 |
| Mechanisms of Carcinogenesis |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Biochem 515, Epid 515 or equivalent |
| This course analyzes and integrates genetics, molecular and cellular factors into mechanisms of carcinogenesis. These factors and their interactions with the environment are applied to hypothesis building and testing, risk assessment and management. Breast cancer is the model for the study. |
|
EHS622 |
| Mechanisms of Developmental Toxicology |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Harris, Craig |
| Prerequisites: Grad Status, Biochem 515 or equiv |
| Integration and analysis of scientific information to enhance understanding and elucidate biochemical and molecular mechanisms in developmental toxicology. Course emphasis is on student discussions of the theoretical and practical aspects of embryology as related to biochemical, physiological and molecular mechanisms of embryotoxicity based on readings from the scientific literature. |
|
EHS623 |
| Mechanisms of Reproductive Toxicology |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Loch Caruso, Rita |
| Prerequisites: Grad Status, Biochemistry, Physiology |
| Analysis and integration of scientific information to enhance understanding of molecular and cellular mechanisms of reproductive toxicity. Emphasis is on student discussion of theoretical and practical aspects of mechanistic studies based on assigned reading from the scientific literature. |
|
EHS624 |
| Mechanisms of Neurotoxicology |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Richardson, Rudy |
| Not offered 2008-2009 |
| Prerequisites: Grad Status, Biochemistry, Physiology |
| Analysis and integration of scientific information to enhance understanding of molecular and cellular mechanisms of neurotoxicity. Emphasis is on student discussion of theoretical and practical aspects of mechanistic studies based on assigned reading from the scientific literature. |
|
EHS625 |
| Environment and the Immune Response |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Mancuso, Peter |
| Prerequisites: EHS 506, EHS 513, or permission of the instructor |
| Environmental and occupational exposures to pollutants and toxicants in air, water, and food, whether synthetic or natural, influence human health by interacting with the hosts immune system. These exposures can either initiate or exacerbate human disease. The course will consist of detailed evaluations of papers, chosen by the students, that explore the impact of environmental and occupational exposures on immunesuppression, autoimmunity, or hypersensitivity. Students will lead discussions, make presentations, and write a grant proposal or a report.
|
|
EHS628 |
| Toxicology Research Analysis and Presentation |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Richardson, Rudy |
| Prerequisites: EHS627 |
| Presentations of research topics from current literature by first year students. Advisors will assist in selection and preparation of materials for presentation. Course is designed to develop oral communication skills for presenting scientific material to peer groups. Presentations followed by discussion and questions. |
|
EHS630 |
| Principles of Nutritional Science |
|
Fall
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Gong, Tzy-Wen L |
| Prerequisites: Biochemistry |
| Integration of biochemical and physiological principles of nutrient utilization, nutrient interactions, and the control and regulation of metabolic processes in humans. |
|
EHS631 |
| Advanced Nutritional Science |
|
Winter
term(s) |
|
4 Credit Hour(s)
|
| Instructor(s):
Cole, Suzanne |
| Prerequisites: EHS 630 |
| In-depth review of recent advances in selected areas of nutrition. Emphasis on topics of current research interest. Topics include vitamin metabolism, mineral bioavailability and analysis, nutrition and immune function, amino acid relationship, drug-nutrient interactions, and nutritional biochemistry and metabolism in altered physiologic conditions. |
|
EHS635 |
| Principles of Laboratory Research Techniques in Nutrition |
|
Winter
term(s) |
|
2-4 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: EHS 630 or Perm. Instr. |
| Discussion and practice of selected biochemical methods used in nutritional research. Emphasis placed on understanding the principles of experimental design and laboratory procedures including diet formulation and on the significance of laboratory results |
|
EHS636 |
| Clinical Nutrition |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Han-Markey, Theresa |
| Prerequisites: EHS 630 |
| Study of clinical nutrition skills with an emphasis on disease pathophysiology and current intervention approaches. Basic nutritional approaches for management of various gastrointestinal diseases such as reflux, ulcer, inflammatory bowel and diverticular disease, rationale, and evidence for efficacy will be taught. Current controversies are briefly introduced. Clinical nutrition screening, assessment, use of clinical laboratory data, and physical assessment are also introduced. Nutritional therapy in various diseases incorporates case study instructional modules. Diseases covered include malnutrition, starvation, metabolic stress, gastrointestinal, cardiovascular, and neoplasm. |
|
EHS637 |
| Advanced Clinical Nutrition |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Han-Markey, Theresa |
| Prerequisites: EHS 636 |
| Applies nutrition support principles to various clinical disease states. Covers topics such as regulation of fluid and electrolytes in nutrition support, acid-base balance, and other aspects of parenteral nutrition. |
|
EHS638 |
| Advanced Clinical Nutrition in Chronic Diseases |
|
Winter
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: EHS 630, EHS 631, EHS 636 (or concurrent enrollment) or equiv |
| Review of recent advances in clinical nutrition in the management of specific chronic disorders and illness. Knowledge and skills of current management issues in patients with cancer, genetic disorders such as cystic fibrosis, organ transplantation, inflammatory bowel disease, neurologic disorders such as Parkinson's and Alzheimer's, and acquired immuno-deficiency syndrome. Issues in management and rationale for treatment approaches in chronic debilitating illnesses, complications of long-term metabolic disorders, and high-risk pregnancy. |
|
EHS639 |
| Obesity and Eating Disorders (Psych 642) |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Mancuso, Peter |
| Metabolic, physiological, and psychological determinants of diet choice and dietary behavior. Disorders in regulation of food intake and different intervention strategies will be discussed. Course integrates readings from experimental literature of both psychology and medicine and provides opportunity to develop and analyze intervention strategies. |
|
EHS640 |
| Nutritional Assessment |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Cole, Suzanne |
| Prerequisites: EHS 630, Nutrition Science |
| Didactic and laboratory presentation of anthropometric, biochemical, dietary and physical activity methods for determining nutritional status across all ages of the life cycle. Students will have the opportunity to identify, plan, and implement a simple nutritional assessment research project, with subsequent data management, analysis and interpretation. |
|
EHS642 |
| Community Nutrition |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Cole, Suzanne |
| Prerequisites: EHS 630 |
| An analysis of community programs with primary attention on goals, objectives, implementation and evaluation. Individualﾒs work on a problem in the area of food assistance or nutrition education programs is carried out under the tutorial guidance of an appropriate staff member. Regular conferences are arranged to measure progress and a report is prepared. |
|
EHS643 |
| Food and Nutrition Policy and Programs |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Perm. Instr. |
| This course is designed to expose students to the history and development of federal nutrition policy, for example, the Dietary Guidelines for Americans, the Food Guide Pyramid and National Food Labeling and Education Act. The legislation, administration and evaluation of federally sponsored public health programs and mandate nutrition services will be reviewed and the implementation at state levels will be discussed. |
|
EHS645 |
| Nutrition Education: Theory and Practice |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Grad Status |
| This advanced course in nutrition education combines both research and practice. The course will address: 1) theories from education, human development, psychology, and communications that guide nutrition education research and practice, 2) theoretical and pragmatic issues in the development and implementation of nutrition education programs, and 3) methods and techniques used to evaluate nutrition education programs. |
|
EHS646 |
| Nutritional Counseling |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
|
| Prerequisites: HBHE 600 |
| This course will be primarily for nutrition students. The course will follow a seminar format, with the instructor and students agreeing on number of sessions for the term. The course will provide the basis of client centered interviewing/counseling as a method to address changes in dietary behaviors, especially those behaviors related to development of chronic diseases. Students will be provided the opportunity to practice counseling techniques
|
|
EHS647 |
| Seminar in Nutrition |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Critical reviews of current literature on selected topics and controversies in nutrition, preparation of abstracts and summary reports, and presentation of summarized information in seminar. |
|
EHS651 |
| International Environmental Management System Standards (Bus School & SNRE) |
|
Fall
term(s) |
|
2 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Prerequisites: Grad Status or Perm. Instr. |
| This course provides a comprehensive framework for the understanding of international management standards as applied to environmental and occupational health, with a focus on the rapid globalization of the regulatory environment in response to international trade. Topics will be the International Standards Organization (ISO) 9000 series standards for production system quality management, the ISO 10000 series standards for quality management auditing, the ISO 14000 series standards for environmental management and environmental system auditing, and the proposed standards for occupational health and safety management systems. Auditing methods will be a primary focus of this course. |
|
EHS652 |
| Evaluation of Chemical Hazards |
|
Fall
term(s) |
|
3-4 Credit Hour(s)
|
| Instructor(s):
Zellers, Edward |
| Prerequisites: Previous or concurrent enrollment in biostatistics course |
| Concepts and techniques related to the evaluation of occupational exposures to gases, vapors, and aerosols. Emphasis on operating mechanisms and practical aspects of industrial hygiene air-monitoring equipment, characterizing exposure distributions, and developing sampling strategies. Lectures, laboratory exercises, demonstrations, problems, technical reports, and reading. Primarily for students in occupational health and safety. |
|
EHS653 |
| Environmental Sampling and Analysis Laboratory
|
|
Winter
term(s) |
|
1-3 Credit Hour(s)
|
| Instructor(s):
Zellers, Edward |
| Prerequisites: EHS 652 or permission of instructor |
| Laboratory and lecture course on equipment, instrumentation, methodologies, and strategies for measuring
environmental chemical and microbiological contaminants. A primary emphasis is placed on air monitoring for human
exposure assessment in the workplace and general environment. Dermal, surface, soil, and water contamination
measurements are also covered. Lectures, laboratories, and demonstrations. Primarily for students in environmental
health sciences with interests in occupational and ambient-environmental exposure assessments for regulatory
compliance and epidemiologic risk estimation. |
|
EHS654 |
| Control of Exposures to Airborne Contaminants |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Vincent, James |
| Prerequisites: Grad status |
| Discussion of the principles of controlling airborne contaminants in working and living environments. It deals with general environmental and local exhaust ventilation for indoor spaces, filtration and emission control for the ambient environment, and personal respiratory protection. Specific topics include: basic properties of air and aerodynamics,
and behavior of airborne contaminants; general dilution and local exhaust ventilation concepts, methods and design; fan performance and selection; air cleaning equipment; ventilation testing, OSHA and EPA standards, indoor air quality, and others. |
|
EHS655 |
| Occupational Injury Prevention |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| Introductory Biostatistics and EpidemiologyThis course will describe the application of injury control principles to occupational injury. A specific focus will be the impact of public policy interventions on injury prevention. The goals of this course are to impart the conceptual framework of injury control applied specifically to occupational injuries, and to acquaint the student with how public policy, as well as policy in the private sector, affect the rate and distribution of occupational injury. Students will be expected to describe major dimensions of occupational injury problem in the U.S.: identify major risk factors associated with occupational injury: understand major approaches to occupational injury prevention: and to recognize the sources and influences of public policy on occupational injury prevention. |
|
EHS656 |
| Research Methods in Occupational Health |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Robins, Thomas |
| Not offered 2008-2009 |
| This course provides an integrated approach to occupational health research design and methodology. Topics include: research problem formulation; choice of study design; source of data; data analysis and strategies; SMR and PMR studies; healthy worker effect; case-control studies of occupational cancer; occupational pulmonary and neurology morbidity studies. |
|
EHS657 |
| Advanced Exposure Assessment |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Meeker, John |
| Prerequisites: EHS507, BIOSTAT503/equivalent, EPID503/equivalent |
| The course will introduce classical, contemporary, and cutting-edge approaches to the estimation of human exposure to environmental and occupational agents as it relates to epidemiology studies as well as risk science, regulatory compliance, exposure source/route apportionment, and susceptibility factors. Qualitative and quantitative methods in exposure science will be covered, including surrogate measures, exposure modeling, and biological markers of exposure, in addition to statistical concepts such as exposure measurement error and efficient study design. |
|
EHS658 |
| Physical Hazards |
|
Fall
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Meeker, John |
| Prerequisites: Graduate Standing or Perm. Instr. |
| Lectures, discussions, demonstrations on the health effects, measurements methods, regulations, and control technologies related to physical health hazards encountered in occupational settings, including temperature extremes, noise, vibration, and lasers and other forms of non-ionizing radiation (rf, microwave, IR, visible, and UV). |
|
EHS659 |
| Occupational Injury Prevention Seminar |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Staff |
| Not offered 2008-2009 |
| The focus of this seminar is on current research related to occupational injury, particularly prevention. It will provide an overview of cutting edge research by having seminar presentations for current investigators in the field of occupational injury research. The goals of the seminar are to introduce the students to current research and to introduce the students to injury researchers who might be able to provide mentorship to student research projects related to occupational injury. |
|
EHS668 |
| Professional Seminar in Occupational Health |
|
Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Meeker, John |
| Seminars in contemporary occupational health topics and issues. Presentations by noted authorities from industry, labor organizations, governments, and academia. |
|
EHS670 |
| Applications in Environmental Epidemiology |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Prerequisites: EPID 601, EPID 655, EHS 656 |
| Students will complete an independent reseach project under faculty supervision. Students will apply epidemiological and statistical methods to the analysis of data from epidemiological, exposure assessment or laboratory studies. This course focuses on the conduct of independent research and sceintfic writing under faculty guidance. Course must be elected for 3 credits. This course is the final course of three, in which students plan their field experience (EHS 659), complete their field experience and present a poster to the department (EHS 600), then conduct data analyses and prepare a research report (EHS 670). It is part of the Capstone experience for Occupational and Environmental Epidemiology Students. |
|
EHS671 |
| Air Pollution Chemistry (AOS 578)
|
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Staff |
| Tropospheric and stratospheric air pollution are discussed following a review of thermochemistry, photochemistry and chemical kinetics. Gaseous and particulate air pollutants are considered in terms of their origins and transformations. |
| This course is cross-listed with AOS578 in the AOS department. |
|
EHS672 |
| Life cycle assessment: Human health and environmental impacts |
|
Fall
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Jolliet, Olivier |
| Prerequisites: None |
| This 3-hour course describes how consumption and products affect environmental risks and impacts on human health and on ecosystems. Based on a life cycle approach, this course will first provide an overview of the impacts generated by consumers and by the students themselves. How to carry out Life Cycle Assessment (LCA ) of products and services will then be presented. For the Life Cycle Impact Assessment phase, a special focus will be given to the characterization of comparative risks of toxics substances on human health and ecosystems. This leads to discussion of the potentials and limitations of LCA compared to other assessment tools such as risk assessment and environmental impact assessment. Practical case studies will be taken from multiple consumption domains, from agriculture and food production up to electronic services. |
| Syllabus for EHS672 (PDF,
30500 bytes, last modified on Tuesday, August 26, 2008
) |
|
EHS680 |
| Environmental Management of Hazardous Substances |
|
Winter
term(s) |
|
3 Credit Hour(s)
|
| Instructor(s):
Batterman, Stuart |
| Prerequisites: Perm. Instr. |
| Contemporary and emerging approaches to pollution and waste management that integrate public health, engineering, economic, and regulatory factors related to hazardous substances. Presentation of site assessment, exposure and risk assessment, and permit application practices, impact assessment in pollution prevention, and risk-cost-benefit analysis. In-depth analysis of selected topics using case studies of ongoing or proposed actions.
|
|
EHS687 |
| Air Quality Seminar |
|
Fall, Winter
term(s) |
|
1 Credit Hour(s)
|
| Instructor(s):
Keeler, Gerald |
| Prerequisites: Perm. Instr. |
| Advanced topics in air quality control and research will be presented by leading experts in the field and by students. Sample areas to be covered include urban air pollution, health effects of air pollutants, tropospheric ozone, acid deposition, global warming, indoor air quality, the Clean Air Act, hazardous pollutant deposition, global transport, and air-surface exchange of pollutants. The course will also emphasize current topics in the field that are of importance to policy makers and regulators. The course is offered both Fall and Winter terms and may be taken more than one. |
|
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