UM SPH Winter Courses

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BIOSTAT449

Topics In Biostatistics

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Statistics 401 or permission of instructor

This course will make use of case studies to discuss problems and applications of biostatistics. Topics will include cohort and case control studies, survival analysis with applications in clinical trials, evaluation of diagnostic tests, and statistical genetics. The course will conclude with a survey of areas of current biostatistical research.

This course is cross-listed with Statistics 449 in the Literature, Science and the Arts department.

BIOSTAT510

Statistical Computer Program Packages

Winter term

3 Credit Hour(s)

Instructor(s): Welch, Kathy

Prerequisites: Biostat 503 or 553 or permission of instructor

Students learn use of several widely used statistical computer program packages such as BMDP, SAS and SPSS. Emphasis placed on relative merits of these packages with respect to types of statistical analyses they perform and their methods of data management.

Syllabus for BIOSTAT510 (PDF, 25352 bytes, last modified on Wednesday, February 01, 2006 )

BIOSTAT513

Application of Regression Analysis to Public Health Studies

Winter term

3 Credit Hour(s)

Instructor(s): Song, Peter Xuekun

Offered every year

Prerequisites: Biostat 503, 553 or Perm. Instr.

Biostat 513 will cover a general overview of linear, logistic, Poisson, and Cox regression. The course will use SPSS as the statistical software.

BIOSTAT523

Biostatistical Analysis for Health-Related Studies

Winter term

3 Credit Hour(s)

Instructor(s): Schaubel, Douglas

Prerequisites: BIOSTAT 553; BIOSTAT 503 w/ instructors permission

A second course in applied biostatistical methods and data analysis. Concepts of data analysis and experimental design for health-related studies. Emphasis on categorical data analysis, multiple regression, analysis of variance and covariance.

BIOSTAT578

Practical Projects

Winter term

1-4 Credit Hour(s)

Instructor(s): Staff

Prerequisites: NONE

Practical projects in consultation and statistical analysis of data in research studies with health investigators. Course requirements include an approved practical work experience related to Biostatistics in consultation with a faculty advisor. May be elected more than once. Enrollment limited to Biostatistics majors with at least two full terms of prior registration.

BIOSTAT602

Biostatistical Inference

Winter term

4 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Biostat 601

Fundamental theory that is the basis of inferential statistical procedures. Point and interval estimation, sufficient statistics, hypothesis testing, maximum likelihood estimates, confidence intervals, criteria for estimators, methods of constructing test and estimation procedures.

Syllabus for BIOSTAT602 (PDF, 19074 bytes, last modified on Friday, February 10, 2006 )

BIOSTAT610

Readings in Biostatistics

Winter term

1-4 Credit Hour(s)

Instructor(s): Staff

Prerequisites: One of Biostat 503, Biostat 524, Biostat 553 or Biostat 601/Biostat 602

Independent study in a special topic under the guidance of a faculty member. May be elected more than once. Enrollment is limited to biostatistics majors.

BIOSTAT646

Data Analysis in Molecular Biology

Winter term

3 Credit Hour(s)

Instructor(s): Qin, Zhaohui

Prerequisites: Graduate Standing and Statistics 400,Biostatistics 523, or Biostatistics 553 or permission of instructor

The course will cover statistical methods used to analyze data in experimental molecular biology. The course will primarily cover topics relating to gene expression data analysis, but other types of data such as genome sequence data that is sometimes analyzed in concert with expression data will also be covered.

This course is cross-listed with Statistics 545 (Home Program) Bioinformatics in the Rackham department.

BIOSTAT651

Applied Statistics II: Extensions for Linear Regression

Winter term

3 Credit Hour(s)

Instructor(s): Kim, Sinae

Prerequisites: BIOSTAT601 and BIOSTAT650

Introduction to maximum likelihood estimation; exponential family; proportion, count and rate data; generalized linear models; link function; logistic and Poisson regression; estimation; inference; deviance; diagnosis. The course will include application to real data.

Syllabus for BIOSTAT651 (PDF, 15241 bytes, last modified on Tuesday, January 31, 2006 )

BIOSTAT653

Applied Statistics III: ANOVA and Linear Mixed Models

Winter term

3 Credit Hour(s)

Instructor(s): Banerjee, Mousumi

Prerequisites: BIOSTAT650 and concurrent enrollment in BIOSTAT651

One-way layout, two-way and higher-way layouts; fixed effects and random effects; multiple comparisons; matching and blocking; balanced and unbalanced designs; weighted least squares; repeated measures; longitudinal and clustered data; linear mixed models; variance components; BLUP; REML. The course will include applications to real data.

BIOSTAT664

Special Topics in Biostastics

Winter term

1-4 Credit Hour(s)

Instructor(s): Zoellner, Sebastian; Tsodikov, Alexander; Rosenberg, Noah

Prerequisites: Permission of instructor

Master's level seminar designed to provide an extensive review of a number of substantive and methods and skill areas in biostatistics. Readings, discussion, and assignments are organized around issues of mutual interest to faculty and students. Reviews and reports on topics required in the areas selected. May be elected more than once.

BIOSTAT666

Statistical Models and Numerical Methods in Human Genetics

Winter term

3 Credit Hour(s)

Instructor(s): Boehnke, Michael L

Prerequisites: Biostat 602 or Perm. Instr.

Introduction to current statistical methods used in human genetics. Topics will include sampling designs in human genetics, gene frequency estimation, the coalescent method for simulation of DNA sequences, linkage analysis, tests of association, detection of errors in genetic data, and the multi-factorial model. The course will include a simple overview of genetic data and terminology and will proceed with a review of numerical techniques frequently employed in human genetics.

Syllabus for BIOSTAT666 (PDF, 7573 bytes, last modified on Wednesday, February 01, 2006 )

BIOSTAT680

Applications of Stochastic Processes I

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biostat 601 and Math 450 or equiv

Conditional distributions, probability generating functions, convolutions, discrete and continuous parameter, Markov chains, medical and health related applications.

Syllabus for BIOSTAT680 (PDF, 56428 bytes, last modified on Wednesday, February 01, 2006 )

BIOSTAT682

Applied Bayesian Inference

Winter term

3 Credit Hour(s)

Instructor(s): Johnson, Timothy

Prerequisites: Biostat 602, Biostat 650 and Biostat 651

Introduction to Bayesian Inference. Bayesian large sample inference, relationship with maximum likelihood. Choice of model, including prior distribution. Bayesian approaches to regression generalized linear models, categorical data, and hierarchical models. Empirical Bayes methods. Comparison with frequentist methods. Bayesian computational methods. Assessment of sensitivity to model assumptions. Emphasis on biomedical applications.

Syllabus for BIOSTAT682 (PDF, 12546 bytes, last modified on Monday, February 06, 2006 )

BIOSTAT685

Elements of Nonparametric Statistics

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biostat 602 or STAT 511, and Biostat 650 or Perm. Instr

First half covers theory and applications of rank and randomization tests: sampling and randomization models, randomization t-test, Wilcoxon rank sum and signed rank tests, Kruskal-Wallis test, asymptotic result under randomization, relative efficiency; second half covers theory and applications of nonparametric regression: smoothing methods, including kernel estimators, local linear regression, smoothing splines, and regression splines, methods for choosing the smoothing parameter, including unbiased risk estimation and cross-validation, introduction to additive models.

Syllabus for BIOSTAT685 (PDF, 68383 bytes, last modified on Tuesday, January 31, 2006 )

BIOSTAT690

Health Applications of Multivariate Analysis

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biostat 650 and Biostat 651 and Math 417 or Perm. Instr.

Techniques of multivariate analysis related to health and biomedical problems. Emphasis on computational techniques and programs with health examples. Tests of significance for one, two or more populations; general linear model; multivariate analyses of variances and covariances; correlation procedures; principal components and discriminant analyses.

Syllabus for BIOSTAT690 (PDF, 14721 bytes, last modified on Tuesday, January 31, 2006 )

BIOSTAT699

Analysis of Biostatistical Investigations

Winter term

4 Credit Hour(s)

Instructor(s): Taylor, Jeremy; Elliot, Michael

Prerequisites: Registration for last term of studies to complete MS or MPH

Identifying and solving design and data analysis problems using a wide range of biostatistical methods. Written and oral reports on intermediate and final results of case studies required.

BIOSTAT800

Seminar in Biostatistics

Winter term

1 Credit Hour(s)

Instructor(s): Staff

Presentations and discussions of current consulting and research problems. May be elected more than once. Enrollment limited to biostatistics majors.

BIOSTAT803

Biostatistics in Cancer Seminar

Winter term

1 Credit Hour(s)

Instructor(s): Taylor, Jeremy

Prerequisites: Perm. Instr.

The purpose of this class is to describe biostatistical research that is occuring in collaboration with cancer researchers, and to provide exposure to the field of cancer research. Activities inlcude seminars on statistical methods in cancer; presentations of cancer research; presentations of articles from statistical literature; discussion of cancer clinical tiral protocals and grant proposals; and visits to research laboratories. Students formally in the training program are expected to enroll in this course every semester. The course is open to students not participating in the training grant. It is open to both PhD and Masters students.

BIOSTAT820

Readings in Biostatistics

Winter term

1-4 Credit Hour(s)

Instructor(s): Staff

Students assigned special topics for literature study under guidance of individual faculty members. May be elected more than once. Enrollment limited to biostatistics majors.

BIOSTAT840

Advanced Topics in Data Analysis

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biostat 650 and Biostat 651

Alternate methods of data analysis useful when data do not fulfill unusual assumptions of statistical tests. Using articles from the literature, students learn methods of data analysis more robust than usual methods and how to choose among them. Focuses on comparison of groups, ANOVA and regression.

BIOSTAT845

Advanced Topics in Times Series Analysis

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biostat 645, Stat 531 or Perm. Instr.

Advanced theory of stationary univariate and multivariate time series. Additional advanced topics such as analysis of non-stationary, non-linear, and/or categorical time series; time-frequency analysis; and statistical methods based on the wavelet transform or related transforms. Application of methods to time series data sets from health research.

BIOSTAT850

Research in Biostatistics

Winter term

2-4 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Research on selected topics involving the application of statistical methods to health problems. May be elected more than once. Enrollment limited to biostatistics majors.

BIOSTAT870

Analysis of Repeated Measurements

Winter term

3 Credit Hour(s)

Instructor(s): Raghunathan, Trivellore

Not offered 2008-2009

Prerequisites: Math 417, Biostat 602, Biostat 651 and one of Biostat 690, Biostat 851, or Biostat 890

Mixed model analysis of variance; multivariate profile analysis; linear mixed effects models with unbalanced designs, time-varying covariates, and structured covariance matrices; maximum likelihood (ML), restricted maximum likelihood (REML), and Bayes estimation and inference; nonlinear mixed effects models.

BIOSTAT875

Advanced Topics in Survival Analysis

Winter term

3 Credit Hour(s)

Instructor(s): Schaubel, Douglas

Not offered 2008-2009

Prerequisites: Biostat 675

Lectures and readings from the literature on advanced topics in survival analysis. Covers regression for censored data, general event-history data and models, competing risks. Statistical, mathematical, and probabilistic tools used in survival analysis are extended for these general problems.

BIOSTAT885

Nonparametric Statistics

Winter term

3 Credit Hour(s)

Instructor(s): Song, Peter Xuekun

Prerequisites: Biostat 601/602 or Perm. Instr.

Theory and techniques of nonparametrics and robustness. M-estimation, influence function, bootstrap, jackknife, generalized additive models, smoothing techniques, penalty functions, projection pursuit, CART.

BIOSTAT890

Multivariate Statistical Models (Stat 640)

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Math 417 and either Stat 511 or Biostat 602 and Perm. Instr.

Derivation of multivariate techniques: multivariate estimation, T, criteria for testing linear hypothesis, test for additional information, testing covariance matrices, factor analysis, growth curves and elementary time series.

Syllabus for BIOSTAT890 (PDF, 70844 bytes, last modified on Tuesday, January 31, 2006 )

BIOSTAT990

Dissertation/Pre-Candidacy

Winter term

1-8 Credit Hour(s)

Instructor(s): Staff

Prerequisites: (1-8 Full term, 1-4 Half term)

Election for dissertation work by doctoral student not yet admitted to status as a candidate.

BIOSTAT995

Dissertation Research for Doctorate in Philosophy

Winter term

1-8 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Admission to Doctoral Program(1-8 Full term, 1-4 Half term)

Election for dissertation work by doctoral student who has been admitted to status as a candidate.

EHS311

Naturally Occuring Biological Toxins

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biology, Chemistry (organic preferred)

Explanation of principles needed to understand sources, adverse effects, mechanism of action, and treatment for exposure to naturally occurring toxins from substances such as mushrooms, herbs, plants, microbes, marine organisms, and insect and animal venom. Implications of bioterrorism will be discussed.

This course is cross-listed with Naturally Occurring Biological Toxins, EHS 311 in the LS&A department.

EHS501

Occupational Environmental Disease

Winter term

2 Credit Hour(s)

Instructor(s): O'Neill, Marie

Prerequisites: EHS 505, 506 or equivalent

Selected topics in the diagnosis, treatment and prevention of environmental and occupational disease, including coverage of toxins, exposures, organ systems, and disease. Lectures and case studies address exposures to solvents, radon, lead and other metals, asbestos and other pneumoconiotic dusts, outdoor air pollution, indoor air quality, and noise. Major health effects and disease categories covered include cancer, respiratory disease, and reproductive health. Prerequisites: basic knowledge of human physiology, and exposure assessment. (These requirements may be taken concurrently with this course).

EHS502

Environmental Health in Developing Areas

Winter term

3 Credit Hour(s)

Instructor(s): Nriagu, Jerome

Not offered 2008-2009

The course provides a review of basic environmental health knowledge and skills and their applications in developing areas of the world; case studies from Africa, South America, and Southeast Asia. Delivery will include lectures, reading assignments individual exercises, and term paper.

EHS504

Genes and the Environment

Winter term

2 Credit Hour(s)

Instructor(s): Franzblau, Alfred

Prerequisites: None.

In past years disease causation frequently was thought of as a "dichotomy" between genes ("nature") and the environment ("nurture"). More recently this view has been replaced with a more holistic perspective that emphasizes the importance of interactions between genes and environmental and/or occupational exposures. The focus of this course will be on interaction between genes and specific environmental and/or occupational exposures. The course will consist of detailed evaluation of specific examples of gene-exposure interaction (e.g., beryllium-related lung disease, peripheral neurotoxicity from organophosphate pesticides, bladder cancer and amine exposure) the underlying science of such examples, medical consequences, potential policy and social implications of current and future scientific knowledge, and review of current and pending legislation that address these issues. The course will meet for one two-hour session per week, and will be conducted in an advanced seminar-style format. Student will be expected to make presentations and lead discussion, in addition to presentations by faculty and outside guests. Student evaluations will be based on written reports, class participation and class presentation.

EHS508

Principles of Risk Assessment

Winter term

2 Credit Hour(s)

Instructor(s): Jolliet, Olivier

Prerequisites: EHS 507, Epidemiology (concurrent enrollment acceptable) or Perm. Instr.

This course is designed to provide the knowledge and skills necessary to understand risk assessment methods. Students will understand the use and limitations of risk assessment in establishing exposure standards, acceptable concentrations, and the environmental criteria for hazardous substances that present a risk of carcinogenic or other health effects and the suitability of risk assessment for such purposes. The basic approaches to environmental risk assessment will be emphasized, including methods for identifying health effects, modeling of health effects, and derivation of risk estimates. Methods for dealing with uncertainties as well as limitations and criticisms of risk assessment methods will be discussed. Specific examples of risk assessments will be analyzed and critiqued.

EHS509

Ecological Toxicology

Winter term

3 Credit Hour(s)

Instructor(s): Basu, Niladri

Prerequisites: University level biology and chemistry

'Ecological Toxicology' is a graduate-level course designed to provide an understanding of how ecological receptors (e.g., fish, mammalian wildlife, birds) are exposed to contaminants and how these organisms toxicologically respond at multiple tiers of biological organization, from cells to individuals to ecosystems. Fundamental concepts in ecological toxicology (source, fate, transport, and toxicity of contaminants) will be covered from both a theoretical and applied perspective. These fundamental concepts will be reinforced by case studies that draw upon historical examples, contemporary topics, and the peer-reviewed scientific literature. The processes by which pollutants are tested, evaluated, regulated, and monitored to ensure ecological health will be critically examined. Humans are an integral component of the ecosystem, and this course will critically explore how ecological toxicology can be used to advance human health.

EHS515

Naturally Occurring Biological Toxins

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biology, Chemistry (organic preferred)

This course is cross-listed with Naturally Occurring Biological Toxins, EHS 311 in the LS&A department.

EHS530

Nutrition in Public Health

Winter term

2 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Principles of normal nutrition and relation of nutrition to health. Designed for graduate students in other programs and schools, especially students in health education, physical education and nursing.

EHS531

Herbs and Dietary Supplements

Winter term

2 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biology

The course will examine the status of the usage, production, claimed effects, mechanism of effects and potential misuse and safety of the major herbs and dietary supplements in the US. The course will carefully review the literature and examine the evidence that support the claimed or alleged effects. The course will also discuss the government and industry rules and regulations and the controversies associated with the use of these products.

EHS540

Maternal and Child Nutrition

Winter term

2 Credit Hour(s)

Instructor(s): Cole, Suzanne

Explores the nutritional requirements and support associated with the physiologic changes of pregnancy, lactation, and fetal, infant, child and adolescent growth. Review of recent nutrition issues and recommendations related to mothers and children.

EHS570

Water Quality Management

Winter term

3 Credit Hour(s)

Instructor(s): Xi, Chuanwu

Principles of science and engineering used in the evaluation and control of water quality. Includes current legislation, types of pollution, sources and nature of pollution, introduction to water quality management practices, water supply and treatment, hydrologic concepts, effects of waste discharge on receiving waters, lake management, and water quality criteria and standards.

EHS571

Water Quality Management Practices

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: EHS 570

Principles and methods in water quality management. Methods, applications, and water quality considerations associated with water reclamation and re-use; soils and sediments as factors in water pollution control; flow regulation for water quality management; economics and institutions in water quality management.

EHS576

Microbiology in Environmental Health

Winter term

3 Credit Hour(s)

Instructor(s): Xi, Chuanwu

Prerequisites: Biology, Grad Standing or Perm. Instr.

GGraduate level course on basic knowledge about microbes in the environment and its impact on public health. Topics will include: - introduction on microbiology; - growth and control of microbes in the environment; - characterization and identification of microbes in the environment; - biofilms and its control; - transmission and persistence of health-related microbes in various environments such as water, air, food, indoor and industrial settings; - microbial transformation of organic and metal contaminants in the environments; - spread of antibiotic resistance in the environment.

EHS578

Practical Projects

Winter term

1-4 Credit Hour(s)

Instructor(s): Staff

Prerequisites: None

Practical Projects in the application of theory and principles of Environmental Health Sciences in public health settings. Course requirements include an approved practical work experience related to Environmental Health Sciences in consultation with a faculty advisor. May be elected more than once. Enrollment limited to Environmental Health Sciences majors with at least two full terms of prior registration.

EHS581

Principles of Radiological Health

Winter term

1 Credit Hour(s)

Instructor(s): Miklos, Joseph

Not offered 2008-2009

Prerequisites: Calculus

Broad principles and practices of radiological health for environmental and occupational health generalists. Basic physics, measurement, control of radiation sources and bioeffects, risks, and control policies. Lectures and demonstrations.

EHS582

Principles of Community Air Pollution

Winter term

3 Credit Hour(s)

Instructor(s): Keeler, Gerald

Discussion of economic, nuisance, and health aspects, emphasizing sources, causes, effects, control measures, and the organization and administration of community control programs.

EHS585

Food Safety Management

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Grad status

Evaluation of Food safety from multiple perspectives, including microbial and chemical (pesticide residues, food packaging materials, inorganic/organic materials) contamination. Identification of methods for estimating exposure to chemicals carried by food. Identification of food services systems and methods for quality control/changing the risks for food contamination. Utilization of HACCP (Hazardous Analysis Critical Control Point) in different food service situations. Provision of managerial level training course for inspection/monitoring of food establishments.

EHS588

Environmental Law (SNRE 475)

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Introduces students to Environmental Law and the impact of the legal process on decisions that affect the environment. Topics include common law tort actions, toxic tort actions, statutory controls of pollution and other environmentally harmful activities. Additional areas include administrative agency structure and performance, Constitutional rights to environmental quality and more.

EHS591

Equity Issues in Environmental Health

Winter term

1 Credit Hour(s)

Instructor(s): Nriagu, Jerome

Not offered 2008-2009

Prerequisites: Grad Status

The course will examine equity issues in environmental health research and practice. Emphasis will be on the sources of inequity (specific environmental hazards), and documentation of environmental injustice using different spatial scales and time frames. It will provide a commentary on the desirability for affected communities to have meaningful input into the design and implementation of environmental health assessment, as well as in the use and communication of the results.

EHS608

Environmental Epidemiology

Winter term

2 Credit Hour(s)

Instructor(s): O'Neill, Marie

Prerequisites: Epid600, Biostat 553 or 503, EHS 506 and 507, 550

This course will serve as an introduction to topics in environmental epidemiology, covering major areas of current inquiry in this field. It will convey the basic tools required to critically read the literature and to develop appropriate study designs in light of intended applications. The class meeting will include lectures and student-led discussions. This course will review epidemiologic methods used in evaluating the health effects of physical, biological and chemical agents in the environment and the available evidence on the health effects of such exposures. We will also consider policy and public health applications of the scientific evidence. Topics include lectures on methodology and major environmental exposures, discussions based on review and critiques of current literature, and presentations by outside experts on specific environmental epidemiology issues of current interest. After taking this course, students should have a better understanding of the scope, limitations, applications and future of environmental epidemiology.

This course is cross-listed with EPID608 in the Epidemiology department.

EHS612

Biochemical and Molecular Toxicology

Winter term

3 Credit Hour(s)

Instructor(s): Harris, Craig

Prerequisites: Biol Chem 515 or equivalent, EHS 511

The objective of this course is to provide an in-depth analysis of the biochemical and molecular pathways altered in cells and organisms through exposure to environmental and therapeutic chemicals. The content is directed toward the needs of doctoral and masters students in the basic biomedical sciences involved in laboratory research projects. Topics will cover areas of modern research emphasis and focus on how chemicals act to disturb cellular processes through interaction with cellular receptors, ion channels, transporters, signal transduction pathways, transcription factors, metabolic pathways, enzymes, cytoskeletal elements and other macromolecular targets. Specific information about the latest theories on the regulation and initiation of cell death, mediation of toxicity through hredox status and oxidative stress, mechanisms of carcinogenesis, genoxicity and immunotoxicology will also be discussed.

EHS616

Introduction to Toxicological Pathology

Winter term

2 Credit Hour(s)

Instructor(s): Philbert, Martin

Prerequisites: Physiology and EHS 511 or equivalent.

This course will provide and introduction to the histologic damage produced by chemical toxicants. A combination of lectures, student-led discussions and slide-reading sessions will be used to integrate concepts of toxicological mechanism, physiology and pathologic outcome. Emphasis will be place on molecular methods and mechanisms used for the diagnosis and investigative toxicological pathology. The pathology associated with chemicals that damage the major organ systems of humans and mammals will be discussed. During the two credit hours of didactic class presentations student will lead discussions on the pathologic effects of chemicals on cells, tissues and organs and the pathophysiologic outcome. This course is intended for advanced graduate students in the life sciences.

EHS621

Mechanisms of Carcinogenesis

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Biochem 515, Epid 515 or equivalent

This course analyzes and integrates genetics, molecular and cellular factors into mechanisms of carcinogenesis. These factors and their interactions with the environment are applied to hypothesis building and testing, risk assessment and management. Breast cancer is the model for the study.

EHS624

Mechanisms of Neurotoxicology

Winter term

2 Credit Hour(s)

Instructor(s): Richardson, Rudy

Not offered 2008-2009

Prerequisites: Grad Status, Biochemistry, Physiology

Analysis and integration of scientific information to enhance understanding of molecular and cellular mechanisms of neurotoxicity. Emphasis is on student discussion of theoretical and practical aspects of mechanistic studies based on assigned reading from the scientific literature.

EHS625

Environment and the Immune Response

Winter term

2 Credit Hour(s)

Instructor(s): Mancuso, Peter

Prerequisites: EHS 506, EHS 513, or permission of the instructor

Environmental and occupational exposures to pollutants and toxicants in air, water, and food, whether synthetic or natural, influence human health by interacting with the hosts immune system. These exposures can either initiate or exacerbate human disease. The course will consist of detailed evaluations of papers, chosen by the students, that explore the impact of environmental and occupational exposures on immunesuppression, autoimmunity, or hypersensitivity. Students will lead discussions, make presentations, and write a grant proposal or a report.

EHS628

Toxicology Research Analysis and Presentation

Winter term

1 Credit Hour(s)

Instructor(s): Richardson, Rudy

Prerequisites: EHS627

Presentations of research topics from current literature by first year students. Advisors will assist in selection and preparation of materials for presentation. Course is designed to develop oral communication skills for presenting scientific material to peer groups. Presentations followed by discussion and questions.

EHS631

Advanced Nutritional Science

Winter term

4 Credit Hour(s)

Instructor(s): Cole, Suzanne

Prerequisites: EHS 630

In-depth review of recent advances in selected areas of nutrition. Emphasis on topics of current research interest. Topics include vitamin metabolism, mineral bioavailability and analysis, nutrition and immune function, amino acid relationship, drug-nutrient interactions, and nutritional biochemistry and metabolism in altered physiologic conditions.

EHS635

Principles of Laboratory Research Techniques in Nutrition

Winter term

2-4 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: EHS 630 or Perm. Instr.

Discussion and practice of selected biochemical methods used in nutritional research. Emphasis placed on understanding the principles of experimental design and laboratory procedures including diet formulation and on the significance of laboratory results

EHS637

Advanced Clinical Nutrition

Winter term

2 Credit Hour(s)

Instructor(s): Han-Markey, Theresa

Prerequisites: EHS 636

Applies nutrition support principles to various clinical disease states. Covers topics such as regulation of fluid and electrolytes in nutrition support, acid-base balance, and other aspects of parenteral nutrition.

EHS638

Advanced Clinical Nutrition in Chronic Diseases

Winter term

2 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: EHS 630, EHS 631, EHS 636 (or concurrent enrollment) or equiv

Review of recent advances in clinical nutrition in the management of specific chronic disorders and illness. Knowledge and skills of current management issues in patients with cancer, genetic disorders such as cystic fibrosis, organ transplantation, inflammatory bowel disease, neurologic disorders such as Parkinson's and Alzheimer's, and acquired immuno-deficiency syndrome. Issues in management and rationale for treatment approaches in chronic debilitating illnesses, complications of long-term metabolic disorders, and high-risk pregnancy.

EHS639

Obesity and Eating Disorders (Psych 642)

Winter term

3 Credit Hour(s)

Instructor(s): Mancuso, Peter

Metabolic, physiological, and psychological determinants of diet choice and dietary behavior. Disorders in regulation of food intake and different intervention strategies will be discussed. Course integrates readings from experimental literature of both psychology and medicine and provides opportunity to develop and analyze intervention strategies.

EHS643

Food and Nutrition Policy and Programs

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: Perm. Instr.

This course is designed to expose students to the history and development of federal nutrition policy, for example, the Dietary Guidelines for Americans, the Food Guide Pyramid and National Food Labeling and Education Act. The legislation, administration and evaluation of federally sponsored public health programs and mandate nutrition services will be reviewed and the implementation at state levels will be discussed.

EHS646

Nutritional Counseling

Winter term

1 Credit Hour(s)

Instructor(s):

Prerequisites: HBHE 600

This course will be primarily for nutrition students. The course will follow a seminar format, with the instructor and students agreeing on number of sessions for the term. The course will provide the basis of client centered interviewing/counseling as a method to address changes in dietary behaviors, especially those behaviors related to development of chronic diseases. Students will be provided the opportunity to practice counseling techniques

EHS647

Seminar in Nutrition

Winter term

1 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Critical reviews of current literature on selected topics and controversies in nutrition, preparation of abstracts and summary reports, and presentation of summarized information in seminar.

EHS653

Environmental Sampling and Analysis Laboratory

Winter term

1-3 Credit Hour(s)

Instructor(s): Zellers, Edward

Prerequisites: EHS 652 or permission of instructor

Laboratory and lecture course on equipment, instrumentation, methodologies, and strategies for measuring environmental chemical and microbiological contaminants. A primary emphasis is placed on air monitoring for human exposure assessment in the workplace and general environment. Dermal, surface, soil, and water contamination measurements are also covered. Lectures, laboratories, and demonstrations. Primarily for students in environmental health sciences with interests in occupational and ambient-environmental exposure assessments for regulatory compliance and epidemiologic risk estimation.

EHS654

Control of Exposures to Airborne Contaminants

Winter term

3 Credit Hour(s)

Instructor(s): Vincent, James

Prerequisites: Grad status

Discussion of the principles of controlling airborne contaminants in working and living environments. It deals with general environmental and local exhaust ventilation for indoor spaces, filtration and emission control for the ambient environment, and personal respiratory protection. Specific topics include: basic properties of air and aerodynamics, and behavior of airborne contaminants; general dilution and local exhaust ventilation concepts, methods and design; fan performance and selection; air cleaning equipment; ventilation testing, OSHA and EPA standards, indoor air quality, and others.

EHS655

Occupational Injury Prevention

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Introductory Biostatistics and EpidemiologyThis course will describe the application of injury control principles to occupational injury. A specific focus will be the impact of public policy interventions on injury prevention. The goals of this course are to impart the conceptual framework of injury control applied specifically to occupational injuries, and to acquaint the student with how public policy, as well as policy in the private sector, affect the rate and distribution of occupational injury. Students will be expected to describe major dimensions of occupational injury problem in the U.S.: identify major risk factors associated with occupational injury: understand major approaches to occupational injury prevention: and to recognize the sources and influences of public policy on occupational injury prevention.

EHS657

Advanced Exposure Assessment

Winter term

3 Credit Hour(s)

Instructor(s): Meeker, John

Prerequisites: EHS507, BIOSTAT503/equivalent, EPID503/equivalent

The course will introduce classical, contemporary, and cutting-edge approaches to the estimation of human exposure to environmental and occupational agents as it relates to epidemiology studies as well as risk science, regulatory compliance, exposure source/route apportionment, and susceptibility factors. Qualitative and quantitative methods in exposure science will be covered, including surrogate measures, exposure modeling, and biological markers of exposure, in addition to statistical concepts such as exposure measurement error and efficient study design.

EHS659

Occupational Injury Prevention Seminar

Winter term

1 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

The focus of this seminar is on current research related to occupational injury, particularly prevention. It will provide an overview of cutting edge research by having seminar presentations for current investigators in the field of occupational injury research. The goals of the seminar are to introduce the students to current research and to introduce the students to injury researchers who might be able to provide mentorship to student research projects related to occupational injury.

EHS668

Professional Seminar in Occupational Health

Winter term

1 Credit Hour(s)

Instructor(s): Meeker, John

Seminars in contemporary occupational health topics and issues. Presentations by noted authorities from industry, labor organizations, governments, and academia.

EHS670

Applications in Environmental Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Prerequisites: EPID 601, EPID 655, EHS 656

Students will complete an independent reseach project under faculty supervision. Students will apply epidemiological and statistical methods to the analysis of data from epidemiological, exposure assessment or laboratory studies. This course focuses on the conduct of independent research and sceintfic writing under faculty guidance. Course must be elected for 3 credits. This course is the final course of three, in which students plan their field experience (EHS 659), complete their field experience and present a poster to the department (EHS 600), then conduct data analyses and prepare a research report (EHS 670). It is part of the Capstone experience for Occupational and Environmental Epidemiology Students.

EHS671

Air Pollution Chemistry (AOS 578)

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Tropospheric and stratospheric air pollution are discussed following a review of thermochemistry, photochemistry and chemical kinetics. Gaseous and particulate air pollutants are considered in terms of their origins and transformations.

This course is cross-listed with AOS578 in the AOS department.

EHS680

Environmental Management of Hazardous Substances

Winter term

3 Credit Hour(s)

Instructor(s): Batterman, Stuart

Prerequisites: Perm. Instr.

Contemporary and emerging approaches to pollution and waste management that integrate public health, engineering, economic, and regulatory factors related to hazardous substances. Presentation of site assessment, exposure and risk assessment, and permit application practices, impact assessment in pollution prevention, and risk-cost-benefit analysis. In-depth analysis of selected topics using case studies of ongoing or proposed actions.

EHS687

Air Quality Seminar

Winter term

1 Credit Hour(s)

Instructor(s): Keeler, Gerald

Prerequisites: Perm. Instr.

Advanced topics in air quality control and research will be presented by leading experts in the field and by students. Sample areas to be covered include urban air pollution, health effects of air pollutants, tropospheric ozone, acid deposition, global warming, indoor air quality, the Clean Air Act, hazardous pollutant deposition, global transport, and air-surface exchange of pollutants. The course will also emphasize current topics in the field that are of importance to policy makers and regulators. The course is offered both Fall and Winter terms and may be taken more than one.

EHS688

Topics in Environmental Health Sciences

Winter term

1 Credit Hour(s)

Instructor(s): Hu, Howard

Seminars in contemporary environmental health topics and issues. Presentations by noted authorities from industry, labor organizations, governments, and academia.

EHS697

Readings

Winter term

1-3 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Perm. Instr

Supervised study/review of a selected topic in environmental health, occupational health, nutrition and/or toxicology. May be elected more than once for a maximum of six credits.

EHS698

Research

Winter term

1-6 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Perm. Instr.

Original research investigation of a special topic in environmental health, occupational health, nutrition and/or toxicology. May be elected more than once for a maximum of six credits.

EHS699

Master's Thesis

Winter term

1 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Perm of Thesis Advisor

This course shall be elected by students enrolled in Masterﾒs degree programs that require a formal written thesis as a condition of program completion. The thesis shall be defended in front of the studentﾒs thesis committee. The course grade will reflect the studentﾒs accomplishments relative to the thesis and its defense. The course is to be elected only once.

EHS717

Toxicological Pathology Laboratory

Winter term

1 Credit Hour(s)

Instructor(s): Philbert, Martin

Prerequisites: EHS 616 or Perm. Instr.

This laboratory course will provide an introduction to the histopathology associated with chemical exposures. Students will perform routine histological maneuvers on tissues from rats treated with ﾓunknownﾔ chemicals. Following microscopic inspection of tissues, students will describe the pathological process produced in each tissue and will identify the class of (or specific) chemical to which the organism was exposed.

EHS728

Current Topics in Toxicology

Winter term

1 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Research presentations at the advanced level focused on mechanisms of toxicity. May be elected more than once

EHS899

Advanced Research

Winter term

1-6 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Perm. Instr.

Original investigations of a specific topic in environmental health, occupational health, nutrition and/or toxicology. Designed for doctoral students performing research prior to passing their qualifying exam. May be elected more than once.

EHS990

Dissertation/Pre-Candidacy

Winter term

1-8 Credit Hour(s)

Instructor(s): Staff

Election for dissertation work by doctoral students not yet admitted to status as candidate.

EHS995

Dissertation Research for Doctorate in Philosophy

Winter term

8 Credit Hour(s)

Instructor(s): Staff

Election for dissertation work by doctoral students who have been admitted to status as candidate.

EPID503

Strategies and Uses of Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Eisenberg, Joseph

Last offered Winter, 2008

Prerequisites: Biostat 503, Grad Status

This course offers an introduction to the principles, concepts, and methods of population-based epidemiologic research. It is intended to be the introductory course for students who are NOT majoring in Epidemiology. The course will be divided into three primary sections. The first section will serve as an introduction to the basic principles of epidemiology and the measures used in epidemiology. The second section will discuss epidemiologic study design (including case-control, cohort studies) and analysis (including bias, confounding, effect modification). The third section will cover special topics that are important to an introductory understanding of epidemiology (including outbreak investigations, screening, and the role of epidemiology in public health.

EPID515

Genetics in Public Health

Winter term

3 Credit Hour(s)

Instructor(s): Kardia, Sharon

Last offered Winter 2008

Prerequisites: Perm. Instr. or two undergraduate genetic courses.

This course is designed for students with a background in biology or genetics that are interested in understanding genetics in public health. This course will provide an in depth examination of genetics in public health including newborn screening diseases and practices, fundamentals of population genetics, and the genetics of common chronic diseases.

EPID516

Genomics in Epidemiology

Winter term

4 Credit Hour(s)

Instructor(s): Peyser, Patricia A

Last offered Winter 2007

Prerequisites: Epid 503 or equivalent; Epid 515 or equivalent; Biostat 503 or equivalent

This course relates genomics to the core public health discipline of epidemiology emphasizing the use of genomics to help describe disease frequency and distribution and to gain insights into biological etiologies. Topics include genetic material in disease, in families and in populations; the investigation of multifactorial traits; model-based linkage analysis; model-free linkage analysis; segregation analysis; allele association and linkage disequilibrium; and gene-gene interactions and gene-environment interactions. Issues related to implementing studies are considered.

EPID519

Introduction to Principles and Methods of Molecular Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Staff

Not offered 2008-2009

Prerequisites: EPID 601

This course presents an introduction to the principles of the molecular techniques used in epidemiologic investigations. Emphasis will be on the development of a general understanding of the techniques and vocabulary necessary to communicate with researchers and laboratory personnel involved in the study of disease both at the individual and population level.

EPID524

AIDS: A Public Health Challenge

Winter term

3 Credit Hour(s)

Instructor(s): Monto, Arnold S

Not offered 2008-2009

Prerequisites: Upper Division or Grad Status

Lectures will describe the fundamental issues necessary for understanding the public health crisis presented by the AIDS epidemiologic, including the virology of HIV, immune response and natural history, provision of care, prevention, legal/ethical issues. Includes opportunity for small group discussion of policy formulation. For those students satisfactorily completing a paper on a special topic in AIDS, an additional credit hour is available.

EPID525

Clinical and Diagnostic Microbiology

Winter term

3 Credit Hour(s)

Instructor(s): Newton, Duane

Last offered Winter 2008

Prerequisites: At least 1 prior microbiology course or permission of the instructor

This course will provide students with an introduction to methods used by clinical microbiology laboratories to recover and identify bacteria, fungi, parasites, and viruses from human clinical specimens. The focus will be on organisms that are clincially relevant and will demonstrate the role of the clinical microbiology laboratory in patient management.

EPID543

Virus Diseases

Winter term

2 Credit Hour(s)

Instructor(s): Gerrard, Sonja

Offered every year

Last offered Winter 2007

Prerequisites: Pathogenic Bacteriology

The nature of viruses including replication, transmission, pathogenesis, pathology, antigenic relationships and preventive measures

EPID545

Viral and Molecular Techniques Laboratory

Winter term

3 Credit Hour(s)

Instructor(s): Marrs, Carl F

Offered every year

Last offered Winter 2008

Prerequisites: Perm. Instr.

Methods, including procedures, employed in the study and identification of viruses and virus diseases, Molecular techniques used in virology, bacteriology, and molecular epidemiology.Techniques covered include PCR, flow cytometry, gel electophoresis, recombinant DNA technology, westerns and bacterial typing procedures.

EPID546

Advanced Virology

Winter term

2-6 Credit Hour(s)

Instructor(s): Staff

Prerequisites: EPID 543 and EPID 545

Advanced laboratory studies of viruses and virus diseases with emphasis upon the application of procedures to investigation. May be elected more than once.

EPID550

Reproductive Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Harlow, Sioban

Last offered Winter, 2008

Prerequisites: Epid 600 or Epid 503

This course will provide an overview of epidemiologic methods for the study of reproductive outcomes including menstruation, fertility, pregnancy loss, birth outcomes, and maternal morbidity and mortality. Measurement of these outcomes, problems of study design, selection of study populations, common biases and problems of sample size calculation will be covered. This course is intended for people with a basic understanding of epidemiologic methods. The course will be limited to a maximum of 20 students. Both male and female reproductive concerns are addressed as well as methodologic issues in domestic and international settings.

EPID555

Globalization and Health

Winter term

2 Credit Hour(s)

Instructor(s): Wilson, Mark L

Last offered Winter 2008

Prerequisites: Students must be admitted to the Global Health IC

This seminar explores the diverse health impacts of economic, environmental, and cultural globalization. The transnational movement of people, technologies, capital, commodities, toxins, pathogens, ideologies and treatments are affecting people's well-being through diverse pathways. Introductory lectures and discussion of readings will explore various topics related to these issues. We will study the forces of globalization, beneficial and harmful health impacts, role in economic development and resource distribution, and implications for public health practice.

EPID562

Advanced Bacteriology Laboratory

Winter term

2-6 Credit Hour(s)

Instructor(s): Staff

Last offered Fall 2006

Prerequisites: EPID 560 and EPID 561 or Perm. Instr.I

Individual laboratory studies of selected topics on bacteria of public health importance. May be elected more than once.

EPID565

Research in Hospital and Molecular Epidemiology

Winter term

1-6 Credit Hour(s)

Instructor(s): Staff

Offered every year

Last offered Winter, 2008

Prerequisites: Perm. Instr.

Investigation of a selected problem planned and carried out by each student. Pertinent literature, investigational approaches, and progress in the investigations are discussed in seminars. May be taken more than once for up to six credits. Usually taken first for one credit. This is the Capstone Course for Hospital and Molecular Epidemiology Students.

EPID570

Socioeconomic Health Inequalities

Winter term

3 Credit Hour(s)

Instructor(s): Lynch, John

Not offered 2008-2009

Prerequisites: Epid 503/601 and Bios 503 or Perm. Instr.

This course will familiarize students with the extensive epidemiological research and concepts that have documented and attempted to explain socioeconomic inequalities in health. Observations of socioeconomic health inequalities are one of the strongest, pervasive and most consistent findings in epidemiological research. The course will mainly focus on socioeconomic health inequalities in the US, but will also draw on evidence concerning cross-national comparisons among industrialized countries and global health inequalities more generally. The course will focus on developing an understanding of how aspects of the way we structure our socioeconomic systems affects the likelihood of exposure to positive and negative risk factors for disease over the lifecourse. Two key conceptual orientations will be presented: 1) how health inequalities develop over the lifecourse, and 2) how health inequalities are produced by multi-level genetic, biological, psychosocial, economic and other contextual factors.

EPID578

Practical Projects in Epidemiology

Winter term

1 Credit Hour(s)

Instructor(s): Staff

A period of elective (i.e., non-required) practical projects for international students in Epidemiology. Students work for at least eight weeks in an approved agency. Course requirements include this approved practical work experience related to the student's field of study plus prior and concurrent consultation with the student's faculty advisor. Restricted to Epidemiology majors with at least two full consecutive terms of enrollment.

EPID582

Molecular Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Foxman, Betsy

Last offered Winter, 2007

Prerequisites: EPID 503 or EPID 601; and EPID 515, or equiv

The rapid development in molecular techniques since the early 1980ﾒs has enhanced the ability of epidemiologists to define and measure both exposures and outcomes. In this course, we will explore the impact of these measures on the design, conduct and analysis of epidemiologic studies by examining successful and unsuccessful applications of these new measurement tools. We will also discuss the ethical issues arising from an enhanced ability to identify individuals with early stage of disease, increased susceptibility or to measure very low levels of exposure in the environment, and sensitize students to the potential conflicts in research ethics arising from collaborative research projects.

EPID595

Foundations of Dental Public Health

Winter term

4 Credit Hour(s)

Instructor(s): Ismail, Amid

This course is the dental public health student's introduction to the discipline. It presents a social and historical context for dental public health, and provides a basis for the more detailed examination of other aspects of the discipline which are covered in other courses. Students will learn about the public agencies and professional organizations involved in dental public health activities, and will have the opportunity to compare and contrast the structure of public health dentistry in the U.S. with that in other countries. Recent activities, projects, and publications in dental public health will be discussed. Practitioners in dental public health need to be able to locate information efficiently, to appraise its value, and to use that information in writing and speaking. They need to be confident in their ability to write clearly and to speak assertively in public. This course aims to provide students with the necessary skills and knowledge needed to locate information, judge its quality, present critical summaries using written and oral communication. The course also allows students to develop confidence in their writing and public speaking. Students will prepare several written projects and oral presentations. The final project will involve the preparation of a mini systematic literature review of a topic chosen by the student, and an oral presentation based on this review.

EPID602

Foundations in infectious disease transmission modeling

Winter term

3 Credit Hour(s)

Instructor(s): Eisenberg, Joseph

Last offered Winter 2008

Prerequisites: EPID 600, BIOSTATS 503, 553, or another course that provides a similar background in probability and statistics

Infectious disease transmission modeling provides a theoretical framework for the field of infectious disease epidemiology, and therefore provides the basis for thinking about study design, data analysis, and decision making on public health policy questions. This course will serve as an introduction to infectious disease transmission modeling, teaching more quantitative concepts of disease transmission. It will cover the basic tools required to both critically read modeling papers and to develop and use models as research tools. Emphasis will be placed on using models to understand infectious disease processes and to evaluate potential control strategies. The class meeting will consist of both lecture material covering conceptual issues and a computer lab to apply these concepts using standard infectious disease models.

EPID605

Infectious Disease Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Wilson, Mark L

Offered every year

Last offered Winter 2008

Prerequisites: EPID 503 or EPID 601 and prior or concurrent enrollment in EPID 515, or equiv

Introduction to disease and transmission characteristics, and the descriptive epidemiology of infectious agents. This course will help students to understand the theoretical basis of pathogen transmission and what factors determine patterns of disease occurrence. Students will learn how to apply this understanding to disease prevention and control.

EPID607

Applied Epidemiology for Public Health Practice

Winter term

3 Credit Hour(s)

Instructor(s): Boulton, Matthew

Offered every year

Last offered Winter 2008

This course will address the role of the epidemiologist in the provision of personal and preventive health services in the public health practice setting. Emphasis will be on developing an understanding of the biomedical basis and applied use of these services with particular attention to communicable disease surveillance, immunizations, and sexually transmitted disease services. The effect of changing funding streams, managed care, and the role of federal, state and local political, health, and community agencies in determining service mix and content will also be discussed. Students will have the opportunity to directly participate in service provision in their area of interest and will be expected to develop a semester project addressing a specific public health practice problem.

EPID608

Environmental Epidemiology

Winter term

2 Credit Hour(s)

Instructor(s): O'Neill, Marie

Offered every year

Last offered Winter 2008

Prerequisites: Epid600, Biostat 553 or 503, EHS 506 and 507, 550

This course is cross-listed with EPID608 in the Epidemiology department.

EPID609

Vaccines in Public Health

Winter term

3 Credit Hour(s)

Instructor(s): Yang, Zhenhua

Last offered Winter 2007

Not offered 2008-2009

Prerequisites: Epid 601 or permission of instructor

Vaccines represent the most cost-effective medial intervention that has made a major effect on mortality reduction and population growth. This course will cover the epidemiological, statistical, biological, microbiologic, immunological principles, approaches and methods used in vaccine development and vaccination program design. Through a detailed discussion of the pathobiology, epidemiology, vaccine, and vaccination program design of a selected group of vaccine preventable diseases, the course will introduce the students to the major types of infectious diseases defined by the types of pathogens, the different transmission mechanisms of infectious diseases, the concept of population transmission dynamics, and the basic types of population effects of vaccination. Current issues and challenges in vaccine development and immunization practice will als be discussed.

EPID610

Epidemiology and Prevention of Oral Diseases

Winter term

4 Credit Hour(s)

Instructor(s): Taylor, George

Philosophy, principles, and methods of study in the epidemiology of oral conditions. Includes measurement techniques, risk factor identification, and disease distribution in populations. The scientific basis for procedures and programs to prevent oral diseases is examined, with emphasis on public health applications. Includes water fluoridation, other fluoride programs, pit-and-fissure sealant, diet, nutrition, oral hygiene, chemotherapeutics, and screening programs. Required for all students in dental public health.

EPID611

Administration in Dental Public Health

Winter term

4 Credit Hour(s)

Instructor(s): Ismail, Amid

The planning, operation, and evaluation of dental public health programs, including quality assurance, budgeting, and legislative issues. Students prepare a research proposal and develop skills in oral presentations. Required for all students in dental public health.

EPID612

Collection and Analysis of Dental Data

Winter term

4 Credit Hour(s)

Instructor(s): Ismail, Amid

Prerequisites: EPID 610 and Biostat 503

Conduct of a dental field survey and analysis of the data collected. Includes establishment of survey aims, survey organization, examination of subjects, processing and analysis of data, preparation and submission of report. Several otherwise free days are required for the field survey, which is usually conducted outside Ann Arbor. Both custom-written data-capture software and commercial statistical software are employed. Particular attention is paid to the special problems presented by dental data in analysis and interpretation. Extensive use of microcomputers is required. Required for all students in dental public health.

EPID613

Problem in Dental Public Health

Winter term

1-4 Credit Hour(s)

Instructor(s): Taylor, George; Ismail, Amid

Prerequisites: Perm. Instr.

Solutions to problems in dental public health can be pursued by students under the tutorial guidance of a faculty member. The problems can be in any aspect of research or administration. Students can also analyze data from existing research databases, and prepare reports intended for publication. Students meet regularly with the faculty supervisor to assess progress throughout the project. May be elected more than once

EPID616

Neuroepidemiology

Winter term

2 Credit Hour(s)

Instructor(s): Haan, Mary

Last offered Fall 2007

Prerequisites: Minimum: Research methods class at advanced master's level, 1 year of statistics or biostatistics.

This course will cover topics in neuroepidemiology as applied to populations, including application of epidemiologic methods and principles to common neurologic outcomes,specific outcomes such as Alzheimer's disease, Parkinson's, stroke, peripheral neuropathy, cognitive impairment, and etiology and prevention of common outcomes including current knowledge from observational and intervention studies. The use of/experience with neuroimaging in population-based studies will be addressed.

EPID617

Social epidemiology II: Social and economic determinants of population health

Winter term

3 Credit Hour(s)

Instructor(s): Galea, Sandro

Offered every year

Last offered Winter 2008

Prerequisites: EPID 514 or permission of instructor

This course rests on the premise that the study of the determinants of health at multiple levels, and their interrelationships, is essential in order to better explain, and potentially predict, the health of populations. Although this course is grounded in an appreciation for the contribution of different disciplines to the study of population health, it focuses on the particular role that epidemiologic perspectives and methods can offer to improve our understanding of population health. As such, this course will be divided into three primary sections. The first section will consider the notion of population health, what we mean by this, and how thinking about population health challenges some of the core methods, and assumptions, of epidemiology. The second section will consider some of the key potential macro-level determinants of population health, and consider the potential role of epidemiologic methods in studying these determinants. The third section will consider epidemiologic methods, their potential, and their limitations in defining population health, understanding its determinants, and assessing the mechanisms through which these determinants influence population health. This course is a combination of didactic lectures and student discussion.

EPID620

The Epidemiology of Women's Health

Winter term

3 Credit Hour(s)

Instructor(s): Sowers, MaryFran

Offered every other year

Last offered Winter 2007

Not offered 2008-2009

Prerequisites: Epid 503, Epid 601 or P.I.

This course will examine sexual differences in biology and physiology as well as gender differences in social roles, occupations, and life experiences that can lead to gender differences in patterns of exposure and disease expression. This course will then consider when and how these gender differences influence the selection and implementation of epidemiologic research methods and areas in which research methods and measurement tools need development. Topics will include 1) the physiology and endocrinology of puberty, the menstrual cycle, menopause, and pregnancy; 2) physiology and endocrinology of gender differences in cardiovascular, immunological, neurological and musculoskeletal systems; 3) womenﾒs social and political role and the theory of womanﾒs double burden, occupational and economic patterns across the lifespan, health care practices across the lifespan, and social status; and 4) the impact of gender on research questions, study design, sampling approaches, recruitment and retention of study participants, questionnaire design and on research approaches.

EPID621

Cancer Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Soliman, Amr

Offered every year

Last offered Winter 2008

Prerequisites: EPID 601 or Perm. Instr.

The course will review the socio-demographic magnitude of cancer, basic concepts of cancer biology and the causes of cancer. Methods for evaluating genetic factors, tobacco, alcohol, radiation, chemicals, pharmaceuticals, viruses and nutrition will be reviewed in lectures and by classroom discussion of selected publications.

EPID622

CANCER EPIDEMIOLOGY IN SPECIAL POPULAITONS

Winter term

1 Credit Hour(s)

Instructor(s): Soliman, Amr

Offered every year

Last offered Winter 2008

Prerequisites: EPID621 CO-REQUISITE

The focus of the course will be on epidemiologic, genetic, environmental, and lifestyle risk factors of cancer in international and ethnically- diverse populations. Topics will include in-depth discussion of incidence, mortality, and survival of cancer in special populations, distinct aspects of environmental, genetic, and lifestyle factors, and research methods for conducting epidemiologic studies on cancer in special populations.

EPID623

Nutritional Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Sowers, MaryFran

Last offered Winter 2007

Not offered 2008-2009

Prerequisites: EPID 503, EPID 601, Biostat 503, Biostat 523

This course will include study in three major areas of nutritional epidemiology: methods of exploring nutrition-disease interrelationships, major epidemiological identified associations between nutritional status and health status, and implications for public health and public health policy in associations between nutritional status and health status.

EPID624

Readings in Epidemiology

Winter term

1-2 Credit Hour(s)

Instructor(s): Staff

Prerequisites: Perm. Instr.

Review of literature on selected subjects under guidance of individual faculty members and through scheduled seminars at which reports are presented. May be elected more than once.

EPID631

TOPICS IN CANCER PREVENTION I

Winter term

1 Credit Hour(s)

Instructor(s): Soliman, Amr

Offered every year

Last offered Winter 2008

Prerequisites: NONE

This multidisciplinary seminar will be taught by several faculty from the School of Public Health, School of Nursing, and the Medical School. Each faculty member will give a presentation followed by discussion of research articles.

Syllabus for EPID631 (PDF, 36130 bytes, last modified on Monday, November 05, 2007 )

EPID632

TOPICS IN CANCER PREVENTION II

Winter term

1 Credit Hour(s)

Instructor(s): Soliman, Amr

Offered every year

Prerequisites: NONE

Syllabus for EPID632 (PDF, 28906 bytes, last modified on Tuesday, November 20, 2007 )

EPID650

Principles and Practice of Preventive Medicine

Winter term

2 Credit Hour(s)

Instructor(s): Boulton, Matthew

Offered every year

Last offered Winter 2008

Prerequisites: none

This course is intended to introduce preventive medicine residents to the principles of preventive medicine and public health via a seminar approach. Individual seminars are facilitated by residency physician faculty and other invited physician faculty who provide guidance and oversight to the presenting resident for a given session. Presentations are based on peer review papers selected by the residents who also facilitate the participation of non physicians enrolled in the course. Presentation are on a broad range of topics including but not limited to emerging infectious diseases, cancer epidemiology, public health genomics, immunizations, cardiovascular disease, and emergency preparedness. Students are evaluated on appropriateness of selected papers for a given topic, presentation quality, faciliation of class discussion, preparation of pertinent questions, and class participation.

EPID655

Field Studies in Epidemiology

Winter term

3 Credit Hour(s)

Instructor(s): Lisabeth, Lynda

Last offered Winter 2008

Prerequisites: EPID 600 or Perm. Instr.

Formulation of study goals, selection of epidemiologic parameters, sampling strategies, questionnaire design and administration, database construction, entry and validation, interpretation of univariate and bivariate results. Student groups design and execute a pilot field study.

EPID657

Field Internship in Epidemiology I

Winter term

1 Credit Hour(s)

Instructor(s): Staff

Offered every year

Last offered Winter 2008

Prerequisites: INDI, Grad Standing and Perm. Instr.

Students register for one credit hour with a faculty member who serves as the departmental internship advisor. Coursework involves identifying and applying for an internship, attending required sessions on Human Subject IRB approval processes and attending a planning session for the EPID 658 presentation to be done the following Fall Term.

EPID659

Applications of Epidemiology

Winter term

2-4 Credit Hour(s)

Instructor(s): Staff

Offered every year

Prerequisites: EPID 601, EPID 655, Perm. Instr.

Application of epidemiological methods and concepts to analysis of data from epidemiological, clinical or laboratory studies. Introduction to independent research and scientific writing under faculty guidance. May be elected more than once for a total credit of not more than four hours. Course must be elected for a total of 4 credits; either elected for 2 credits each during 2 different terms or for 4 credits during a single term. This is the Capstone Course for General Epid and International Health Students.

EPID664

Field Methods in Epidemiology for Developing Countries

Winter term

3 Credit Hour(s)

Instructor(s): Soliman, Amr

Offered every year

Last offered Winter 2008

Prerequisites: Epid 503 or Epid 601

This course is developed for students and researchers interested in pursuing collaborative epidemiologic research in international settings. The course will focus on steps and procedures for setting up and conducting international epidemiologic studies. Topics will include relationship between research groups and host country policy makers and collaborators, cultural and logistical differences between research studies in the U.S. and international settings. Other topics will include developing and