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Charles Burant

Charles Burant, MD, PhD

Dr. Robert C. and Veronica Atkins Professor of Metabolism

Professor, Environmental Health Sciences

WK Kellogg Eye Center, Brehm Tower      Vcard icon
1000 Wall Street, Room 6309
Ann Arbor, Michigan 48105-5714

E-mail: burantc@umich.edu

Website(s): The Burant Lab

Professional Summary

Charles Burant is professor of internal medicine, Section of Metabolism, Endocrinology, and Diabetes. He holds the Robert C. and Veronica Atkins Professor of Metabolism endowed chair. His clinical interests are in the care of patients with obesity, type 2 diabetes, and related conditions. Burant's research program integrates molecular phenotyping (genomics, transcriptomics, proteomics, and transcriptomics) with dietary, clinical, and biobehavioral phenotypes to understand the development of obesity, insulin resistance, and diabetes in both people and in animal models. He also has an interest in the intermediary metabolism of ?-cells and how nutrients and insulin resistance modulate insulin secretion.

Burant directs the Michigan Metabolomics and Obesity Center (MMOC), the umbrella organization for the NIH-funded Nutrition Obesity Research Center and Michigan Regional Comprehensive Metabolomics Resource Core. These centers provide infrastructure for human and animal studies related to metabolic diseases. In addition, the center coordinates the activities of the Investigational Weight Management Clinic which integrates cutting-edge clinical care with phenotypic measures of individuals before and after intensive weight loss with a goal to understand the weight loss factors that prevent diabetes and drivers of weight regain in previously obese patients.

Burant earned his BS in biochemistry at the University of Wisconsin, Madison, in 1979. He earned an MS in environmental toxicology at the University of Wisconsin, Madison, in 1981. He earned an MD in medicine at the Medical University of South Carolina in 1987. He earned a PhD in molecular and cell biology at the Medical University of South Carolina in 1987.

Research Interests & Projects

Dr. Burant's research laboratory investigates the mechanisms of insulin resistance and utilizes animal models of diabetes to identify pathways important in understanding diabetes progression. Additionally, his lab also studies adult pancreatic progenitor cells and how they might be used to generate new insulin secreting beta-cells.