Carl F. Marrs, Ph.D.

Associate Professor, Epidemiology

5116 SPH II
1415 Washington Heights
Ann Arbor, Michigan 48109-2029

Office: (734) 647-2407; Fax: 734-764-3192

E-mail: cfmarrs@umich.edu

Curriculum Vitae (PDF, 182,179 KB)

Professional Summary

Associate Professor, Department of Epidemiology, University of Michigan School of Public Health.
Member, Executive Committee, Public Health Genetics Interdepartmental Concentration Faculty Member, Molecular Mechanisms of Microbial Pathogenesis Training Grant, University of Michigan School of Medicine.
Faculty Member, Interdisciplinary Program in Infectious Diseases Training Grant, University of Michigan School of Public Health.
Chair, Epidemiology Admissions Committee.
Associate Chair, University of Michigan Institutional Biosafety Committee.
Head, Evolution of Infectious Disease Discussion Group.
Member Executive Committee, Undergraduate Microbiology Concentration Program.
Member, Program Committee for the Center for Molecular and Clinical Epidemiology of Infectious Diseases

Courses Taught

EPID399: Independent Research for Undergraduates
EPID460: Introduction to Bacterial Pathogenesis    Syllabus (PDF)
EPID511: Introduction to Public Health Genetics    Syllabus (PDF)
EPID545: Viral and Molecular Techniques Laboratory
EPID560: Mechanisms of Bacterial Pathogenesis    Syllabus (PDF)
EPID682: Current issues in Molecular Epidemiology of Infectious Diseases
EPID565: Research in Hospital and Molecular Epidemiology
EPID624: Readings in Epidemiology

Education

Ph.D., Molecular Biology, University of Wisconsin, 1982
B.S., Chemistry, University of Washington, 1975

Research Interest & Projects

Molecular epidemiologic approaches to urinary tract infection gene discovery.
Molecular epidemiology of Group B Streptococcus and Streptococcus mutans.
Virulence related genetic variation of Mycobacterium tuberculosis strains.
Haemophilus influenzae genes associated with acute otitis media and COPD.
Transmission dynamics and antibiotic resistance in Escherichia coli.
Antibiotic resistance gene resistance transfer in biofilms.
Public health genetics.

Selected Publications

Zhang, L., U. Reddi, U. Srinivasan, S. Li, S. Borchardt, P. Pillai, P. Mehta, A. Styka, J. DeBusscher, C.F. Marrs and B. Foxman." (2008). Combining microarray technology and molecular epidemiology to identify genes associated with invasive group B Streptococcus. Interdisciplinary Journal of Infectious Diseases

Foxman, B., Gillespie, B., Manning, S., Marrs, C.F. (2007). Risk factors for GBS colonization: potential for different transmission systems by capsular type. Annals of Epidemiology, 17, 854-862.

Juliao, P.C., Marrs, C.F., Xie, J., Gilsdorf, J.R. (2007). Histidine auxotrophy in commensal and disease-causing non-typeable Haemophilus influenzae. Journal of Bacteriology, 189, 4994-5001.

Berrens, Z.J., Marrs, C.F., Pettigrew, M.M., Sandstedt, S.A., Patel, M., Gilsdorf, J.R. (2007). Genetic diversity of paired middle ear and nasopharynx non-typeable Haemophilus influenzae isolates from children with acute otitis media. Journal of Clinical Microbiology, 45, 3764-3767.

Hebert, A.M., Talarico, S., Yang, D., Durmaz, R., Marrs, C.F., Zhang, L., Foxman, B., Yang, Z. (2007). DNA Polymorphisms of Mycobacterium tuberculosis pepA and PPE18 Genes among Clinical Strains: Implications for Vaccine Efficacy. Infection and Immunity, 75, 5798-5805.

Xie, J., L. Zhang, B. Foxman, C.F. Marrs. (2006). Molecular epidemiologic identification of Escherichia coli genes potentially involved in movement from the intestinal tract to the vagina and bladder. Journal of Clinical Microbiology, 44, 2434-2441.

Blahna, M.T., C.A. Zalewski, J. Reuer, G. Kahlmeter, B. Foxman, and C.F. Marrs. (2006). The role of horizontal gene transfer in the spread of trimethoprim-sulfamethoxazole resistance among uropathogenic Escherichia coli in Europe and Canada. Journal of Antimicrobial Chemotheraphy, 57, 666-672.

Foxman, B., L. Zhang, J.S. Koopman, S.D. Manning and C.F. Marrs. (2005). Choosing an appropriate bacterial typing technique for epidemiologic studies. Epidemiologic Perspectives and Innovations, 25 Nov 2005, 2:10.

Marrs, C.F., L. Zhang, and B. Foxman. (2005). Escherichia coli mediated urinary tract infections: Are there distinct uropathogenic E. coli (UPEC) pathotypes? FEMS Microbiology Letters, 252, 183-190.

Zhang, L., U. Srinivasan, C.F. Marrs, D. Ghosh, J.R. Gilsdorf, and B. Foxman. (2004). Library on a slide: a new microarray experimental paradigm for comparative genomics of bacteria. BMC Microbiology, 4:12

Professional Affiliations

American Association for the Advancement of Science
American Society for Microbiology
Editorial Boards of Infection and Immunity, and Journal of Clinical Microbiology