Dana Dolinoy, Ph.D.

Dana Dolinoy

Associate Professor, Environmental Health Sciences

6638 SPH Tower      Vcard icon
1415 Washington Heights
Ann Arbor, Michigan 48109-2029

Fax: (734) 936-7283

E-mail: ddolinoy@umich.edu

Website(s): Dolinoy Lab Website

Curriculum Vitae (PDF)

Professional Summary

Dr. Dana Dolinoy is Associate Professor of Environmental Health Sciences at the University of Michigan School of Public Health (UM SPH) and leads the Environmental Epigenetics and Nutrition Laboratory at UM SPH, which investigates how nutritional and environmental factors interact with epigenetic gene regulation to shape health and disease.  Dr. Dolinoy holds a BA in environmental sciences and policy and Spanish from Duke University, an MSc in environmental sciences and engineering from the Harvard School of Public Health, and a PhD in Genetics and Genomics and Integrated Toxicology from Duke University.  She serves on the Editorial Board for the Journal of Nutritional Biochemistry as well as Epigenetics, Environmental and Molecular Mutagenesis, and Toxicological Sciences, and is an active member of the Society of Toxicology (SOT), the Environmental Mutagen and Genomics Society (EMGS), and the American Society for Nutrition (ASN), and will serve as Chair of the 2015 Gordon Research Conference (GRC) in Molecular & Cellular Mechanisms of Toxicity. In 2011, Dr. Dolinoy received the Norman Kretchmer Memorial Award from ASN and the Classic Paper of the Year Award from Environmental Health Perspectives for Dolinoy et al. "Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome." In 2012, she was the recipient of the Association of Schools of Public Health (ASPH)/Pfizer Research Award for the article, "An Expression Microarray Approach for the Identification of Metastable Epialleles in the Mouse Genome." This work was cited as a model approach that may allow for directly assessing the role of early nutritional and environmental exposures in human adult disease.  

Courses Taught

EHS601: Foundations in Environmental Health Sciences
EHS660: Environmental Epigenetics and Public Health
EHS801: Research and Communication in the Environmental Health Sciences

Education

Ph.D., Genetics and Genomics & Integrated Toxicology and Environmental Health, Duke University, 2007
M.Sc., Environmental Health and Risk Management, Harvard University, 2003
B.A., Environmental Sciences and Policy & Spanish, Duke University, 1998

Selected Publications

Search PubMed for publications by Dana Dolinoy >>

Marchelwicz E.H., Anderson O.S., Dolinoy D.C. (May, 2014). Early life exposures and the epigenome - interactions between nutrients and the environment In Emily Ho and Frederick Domann (Ed.) Role of Nutrition and Metabolism on Epigenetic Regulation Taylor & Francis Group, CRC Press.

Weinhouse C., Anderson O.S., Bergin I.L, Vandenbergh D.J., Gyekis J.P., Dingman M.A., Yang J., Dolinoy D.C. (May, 2014). Dose-dependent incidence of hepatic tumors following perinatal bisphenol A exposure Environmental Health Perspectives

Faulk C., Liu K., Barks A., Goodrich J.M., Dolinoy D.C. (April, 2014). Longitudinal epigenetic drift in mice perinatally exposed to lead (Pb) Epigenetics

Nahar MS, Liao C, Kannan K, Dolinoy DC (February, 2013). Fetal Liver Bisphenol A Concentrations and Biotransformation Gene Expression Reveal Variable Exposure and Altered Capacity for Metabolism in Humans Journal of Biochemical and Molecular Toxicology

Goodrich J.M., Basu N., Franzblau A., Dolinoy D.C. (April, 2013). Mercury biomarker levels and gene specific methylation in the Michigan Dental Association Cohort Environmental and Molecular Mutagenesis

Anderson OS, Peterson KE, Sanchez BN, Zhang Z, Mancuso P, Dolinoy DC FASEB J. 2013 Jan 23. (January, 2013). Perinatal bisphenol A exposure promotes hyperactivity, lean body composition, and hormonal responses across the murine life course The FASEB Journal

Faulk C, Barks A, Dolinoy DC (January, 2013). Phylogenetic and DNA methylation analysis reveal novel regions of variable methylation in the mouse IAP class of transposons BMC Genomics

Vandenberg LN, Ehrlich S, Belcher SM, Ben-Jonathan N, Dolinoy DC, Hugo ER, Hunt PA, Newbold RR, Rubin BS, Saili KS, Soto AM, Wang H, vom Saal FS (December, 2013). Low dose effects of bisphenol A: An integrated review of in vitro, laboratory animal and epidemiology studies Endocrine Disruptors

Weinhouse C., Anderson O.S., Jones T.R., Kim J., Liberman S.A., Nahar M.S., Rozek L.S., Jirtle R. L., Dolinoy D.C. (2011). An expression microarray approach for the identification of metastable epialleles in the mouse genome Epigenetics, 6(9)

Dolinoy D.C., Weinhouse, C., Jones, T.R., Rozek, L.S., Jirtle, R.L. (2010). Variable histone modifications at the A(vy) metastable epiallele. Epigenetics, 5(7), 1-8.

Professional Affiliations

2005 - Present: Member, Society of Toxicology
2006 - Present: Member/Chair Epigenetics Special Interest Group, Environmental Mutagen and Genomics Society
2008 - Present: Faculty Member, Michigan Metabolomics and Obesity Center (MMOC)
2009 - Present: Faculty Member, UM Comprehensive Cancer Center
2011 - Present: Member, American Society for Nutrtion (ASN)
2013 - 2015: Chair, 2015 Gordon Research Conference on Cellular and Molecular Mechanisms of Toxicity
2013 - Faculty Member, Momentum Center: Driving Discovery to End Childhood Obesity
2012 - Member, The DOHaD (Developmental Origins of Health and Disease) Society

Videos


Mice exposed to BPA by mothers show unexpected characteristics

Recent News Items

  • "Lead linked to obesity in mice exposed by mothers," ScienceDaily, August 08, 2014
  • "BPA linked to liver cancer in mice," philly.com, February 03, 2014
  • "Changes in Genetic Function in Brain Linked to Alzheimer's," Aging Well, May 21, 2012
  • "BPA makes male mice less macho ," Science News, July 30, 2011
  • " DNA referees," L.A. Times - online, May 03, 2010
  • "Can you master your own epigenetics?," L.A. Times - online, May 03, 2010
  • "Media coverage of the University of Michigan: Are You Really What You Eat? ," MichiganToday.umich.edu, April 14, 2010
  • "Are You Really What You Eat?," Washingtonian.com, April 01, 2010
  • "Please explain: Epigenetics," Wnyc.org, December 04, 2009