Professional Summary
Dr. Dvonch's work focuses on the exposure assessment, source identification, and health effects of air pollutants. He obtained a B.S. in Chemistry in 1992. In 1994, he earned an M.S. in Environmental Health Sciences, and subsequently a Ph.D. in Environmental Health Sciences in 1998. Dr. Dvonch serves as Center Exposure Assessment Scientist for the Michigan Center for the Environment and Children's Health, and collaborates on several other large multi-disciplinary projects focused on environmental exposures and their related effects on health.
Courses Taught
EHS582: Principles of Community Air Pollution
EHS615: Water Quality and Human Health in the Great Lakes Basin
Education
Ph.D., Environmental Health Sciences, University of Michigan, 1998
M.S., Environmental Health Sciences, University of Michigan, 1994
B.S., Chemistry, University of Michigan, 1992
Research Interests & Projects
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Dr. Dvonch's work focuses on the exposure assessment, source identification, and health effects of air pollutants. He obtained a B.S. in Chemistry in 1992. In 1994, he earned an M.S. in Environmental Health Sciences, and subsequently a Ph.D. in Environmental Health Sciences in 1998. Dr. Dvonch collaborates on several large multi-disciplinary projects focused on environmental exposures and their related effects on health.... More >> |
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Goal: To develop a PM2.5 extraction protocol suitable for in vitro mechanistic studies; to develop an in vitro assay of PM2.5 effect on respiratory epithelial cells; to determine variation in epithelial cellular responses by PM composition profile using sample filters collected at different geographic locations representing 8 different mixtures of PM2.5 emission sources and investigate interactive effects with rhinovirus.... More >> |
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Goal: To quantify the collocated collection efficiency of the EPA modified SEAS II slurry sampler. To investigate the SEAS II collection efficiency of size segregated aerosols for use in source apportionment studies. ... More >> |
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Goal: To elucidate the underlying patho-physiological mechanisms linking air pollution with impaired arterial reactivity; to clarify the health significance of air pollution-mediated arterial vasoconstriction.... More >> |
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Goal: To provide insight into toxicological mechanisms of PM-induced cardiopulmonary effects, particularly as they relate to susceptible subpopulations; and generate toxicological data to directly correspond to epidemiology and exposure assessment data from concurrent studies being conducted at one of the project locations.... More >> |
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Goal: To conduct a pilot study to demonstrate the feasibility of investigating the effect of concentrated ambient PM2.5 inhalation upon coronary vascular function determined by cardiac positron emission tomography.... More >> |
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Goal: To study the effect of PM2.5 pre-exposure on blood pressure and vascular function following angiotensin II infusion; and to investigate the role of vasoconstrictor mechanisms activated by ROS in response to PM2.5 pre-exposure.... More >> |
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Goal: To demonstrate that short-term concentrated ambient coarse PM (CAP) inhalation (1) triggers pro-vasoconstrictive vascular dysfunctions related to (mediated by) CV autonomic imbalance; and (2) that these responses occur in African American and White adults alike following exposure to both urban and rural coarse PM; and (3) to elucidate the constituents/sources responsible for the CV responses and to perform detailed characterizations of differences in rural vs. urban coarse PM to improve the epidemiological understanding of coarse PM.... More >> |
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Goal: To assess community member's perceptions of the built environment in Detroit, MI and its impact on prevention of cardiovascular disease; to assess community member's perceptions and knowledge about the built environment and impact on physical activity, dietary practices, and obesity; to design and implement a pilot study around potentially modifiable aspects of the built environment to improve community cardiovascular health.... More >> |
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Goal: To quantify the levels of speciated ambient Hg and Hg deposition (wet and dry) at two sites: Chicago, IL and Holland, MI; to investigate the transport, transformation and deposition of Hg from an urban source region to downwind receptor locations across southern Lake Michigan; to determine the spatial and temporal scales for speciated ambient Hg transport and chemistry downwind from an urban area, across southern Lake Michigan.... More >> |
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Goal: To investigate and quantify the sources contributing to atmospheric mercury deposition at four receptor sites in Illinois. ... More >> |
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Goal: To investigate spatial gradients in the deposition of atmospheric mercury across south Florida; and to determine the sources and source locations contributing to the deposited mercury. ... More >> |
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Goal: To address the recommendations to States by USEPA regarding Mercury Reduction Programs, including: 1) identification of the potential air emission sources or source categories contributing to local and regional atmospheric mercury deposition, as well as, 2) the support of long-term atmospheric mercury monitoring networks, in Michigan. ... More >> |
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Goal: To investigate as a primary endpoint if atorvastatin 40 mg/d for 3 weeks is capable of significantly mitigating the vascular endothelial dysfunction due to acute 1-hr exposure to environmental tobacco smoke.... More >> |
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Selected Publications
Search PubMed for publications by J. Tim Dvonch >>
Dvonch, J.T., Keeler, G.J. and Marsik, F.J. (2005). The influence of meteorological conditions on the wet deposition of mercury in southern Florida. Journal of Applied Meteorology, 44, 1421-1435.
Lewis, T.C, Robins, T.G., Dvonch, J.T., Keeler, G.J., Yip, F.Y., Mentz, G.B., Lin,X., Parker, E.A., Israel, B.A., Gonzalez, L. and Hill, Y. (2005). Air pollution associated changes in lung function among asthmatic children in Detroit. Environmental Health Perspectives, 113, 1068-1075.
Gilliland, F., Avol, E., Kinney, P., Jerret, M., Dvonch, T., Lurmann, F., Buckley, T., Breysse, P., Keeler, G., De Villiers, T. and McConnell, R. (2005). Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives, 113, 1447-1454.
Schulz, A.J., Kannan, S., Dvonch, J.T., Israel, B.A., Allen, A., James, S.A., House, J.S., and Lepkowski, J. (2005). Social and physical environments and disparities in risk for cardiovasular disease: the Healthy Environments Partnership conceptual model. Environmental Health Perspectives, 113, 1068-1075.
Dvonch, J.T., Brook, R.D., Keeler, G.J., Rajagopalan, S., D'Alecy, L, Marsik, F.J., Morishita, M., Yip, F.Y., Brook, J.R., Timm, E.J., Wagner, J. and Harkema, J.R. (2004). Effects of concentrated fine ambient particles on rat plasma levels of asymmetric dimethylarginine. Inhalation Toxicology, 16, 473-480.
Graney, J.R., Dvonch, J.T. and Keeler, G.J. (2004). Use of multi-element tracers to source apportion mercury in south Florida aerosols. Atmospheric Environment, 38, 1715-1726.
Yip, F.Y., Keeler, G.J., Dvonch, J.T., Robins, T.G., Parker, E.A., Israel, B.A. and Brakefield-Caldwell, W. (2004). Personal exposures to particulate matter among children with asthma in Detroit, Michigan. Atmospheric Environment, 38, 5227-5236.
Morishita, M., Keeler, G.J., Wagner, J.G., Marsik, F.J., Timm, E.J., Dvonch, J.T. and Harkema, J.R. (2004). Pulmonary retention of particulate matter is associated with airway inflammation in allergic rats exposed to air pollution in urban Detroit. Inhalation Toxicology, 16, 663-674.
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