Lawrence F. Bielak, D.D.S., M.P.H.

Assistant Research Scientist

M5515 SPH II
1415 Washington Heights
Ann Arbor, Michigan 48109-2029

Office: (734) 647-4162; Fax: (734) 998-6837

E-mail: lfbielak@umich.edu

Education

M.P.H., University of Michigan, 1993
D.D.S., University of Michigan, 1976
B.A., Mathematics, Wayne State University, 1972

Research Interest & Projects

Epidemiology of subclinical coronary atherosclerosis; clinical epidemiology; validity studies; measurement and quality control issues. Dr. Bielak is involved in the following projects: Epidemiology of Coronary Artery Calcification Study; Genetic Epidemiology Network of Arteriopathy; Joint Determinants of Bone Density and CVD Calcification. Genome-Wide Search for Cardiovascular Gene-Environment Interactions.

Selected Publications

Sun, Y.V., Bielak, L.F., Peyser, P.A., Turner, S.T., Sheedy, P.F. II, Boerwinkle, E., Kardia, S.L.R. (May 2008). Application of machine learning algorithms to predict coronary artery calcification with a sibship based design. Genetic Epidemiology, 32(4), 350-360.

Mitchell, McArdle, Shen, Rampersaud, Pollin, Bielak, Jaquish, Douglas, Roy-Gagnon, Sack, Naglieri, Hines, Horenstein, Chang, Post, Ryan, Brereton, Pakzy, Sorkin, Damcott, O'Connell, Mangano, Corrretti, Vogel, Herzog, Weir, Peyser, Shuldiner (May 2008). The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. American Heart Journal, 115(5), 823-828.

Roy-Gagnon, M.H., Weir, M.R., Sorkin, J.D., Ryan, K.A., Sack, P.A., Hines, S., Bielak, L.F., Peyser, P.A., Wendy Post, W., Mitchell, B.D., Shuldiner, A.R., Douglas, J.A. (April 2008). Genetic influences on blood pressure response to the cold pressor test: Results from the Heredity and Phenotype Intervention (HAPI) Heart Study. Journal of Hypertension, 26(4), 729-736.

Bielak, L.F., Yu, P.F., Ryan, K.A., Rumberger, J.A., Sheedy, P.F. II, Turner, S.T., Post, W., Shuldiner, A.R., Mitchell, B.D., Peyser, P.A. (February 2008). Differences in prevalence and severity of coronary artery calcification between two non-Hispanic white populations with diverse lifestyles. Atherosclerosis, 196(2), 888-895.

Schmermund, A., Lehmann, N., Bielak, L.F., Yu, P., Sheedy, P.F. II, Cassidy-Bushrow, A.E., Turner, S.T., Moebus, S., Mohlenkamp, S., Stang, A., Mann, K., Jockel, K.H., Erbel, R., Peyser, P.A. (May 2007). Comparison of subclinical coronary atherosclerosis and risk factors in unselected populations in Germany and US-America. Atherosclerosis, 195(1), e207-e216.

Cassidy-Bushrow, A.E., Bielak, L.F., Sheedy, P.F. II, Turner, S.T., Kullo, I.J., Lin, X., Peyser, P.A. (2007). Coronary artery calcification progression is heritable. Circulation, 116, 25-31.

Shen, H., Bielak, L.F., Streeten, E.A., Ryan, K.A., Rumberger, J.A., Sheedy, P.F. II, Shuldiner, A.R., Peyser, P.A., Mitchell, B.D. (April, 2007). Relationship between Vascular Calcification and Bone Mineral Density in the Old-Order Amish. Calcified Tissue International, 80(4), 244-250.

Post, W., Bielak, L.F., Ryan, K.A., Cheng, Y.C., Shen, H., Rumberger, J.A., Sheedy, P.F. II, Shuldiner, A.R., Peyser, P.A., Mitchell, B.D. (February, 2007). Determinants of coronary artery and aortic calcification in the Old Order Amish. Circulation, 115(6), 717-724.

Messika-Zeitoun, D., Bielak, L.F., Peyser, P.A., Sheedy, P.F., Turner, S.T., Nkomo, V.T., Breen, J.F., Maalouf, J., Scott, C., Tajik, A.J., Enriquez-Sarano, M. (March, 2007). Aortic Valve Calcification. Determinants and Progression in the Population Arteriosclerosis, Thrombosis, and Vascular Biology, 27(3), 642-648.

Coutinho, T.D.A., Turner, S.T., Peyser, P.A., Bielak, L.F., Sheedy, P.F. II, Kullo, I.J. (January, 2007). Associations of serum uric acid with markers of inflammation, metabolic syndrome, and subclinical coronary atherosclerosis American Journal of Hypertension, 20(1), 83-89.