Professional Summary
1968-1978 Extension and Public Health Nutritionist in Kansas, Oklahoma, Iowa 1978-1980 Research Coordinator, Muscatine Coronary Risk Factor Project, Pediatric Cardiology, Univ. of Iowa 1986-1987 Assistant Professor, Division of Nutritional Sciences, Cornell University 1987-1992 Assistant Professor, Department of Epidemiology, University of Michigan School of Public Health 1992-1996 Associate Professor, Department of Epidemiology, University of Michigan School of Public Health 1995-1999 Adjunct Associate Professor, Obstetrics and Gynecology, University of Michigan 1995-present Adjunct Professor of Obstetrics and Gynecology, UMDNJ 1996-present Professor, Department of Epidemiology, University of Michigan School of Public Health 1999-Present Adjunct Professor, Obstetrics and Gynecology, University of Michigan 1999-Present Adjunct Professor, Internal Medicine, University of Michigan
Courses Taught
EPID552: Epidemiology of Chronic Diseases
EPID620: The Epidemiology of Women's Health
EPID623: Nutritional Epidemiology
EPID 620: Epidemiology of Womens Health
Education
Ph.D., Epidemiology, University of Iowa, 1984
M.S., Nutrition, Oklahoma State University, 1973
B.A., Nutrition, Emporia State University, 1968
Post-doctoral Fellow, Endocrine/Epidemiology, University of Iowa, 1985
Research Interest & Projects
NIH Perimenopause, Bone and Arthritis in African Americans (also known as SWAN-Michigan)
The major goals of project are to characterize the impact of menopause among Caucasian and African American women in relation to heart disease, glucose metabolism, bone status, arthritis and blood pressure.
Lead Mobilization and Bone Turnover in Pregnancy/Lactation
The major goals of this project is to describe the impact of bone turnover on lead mobilization and health outcomes in pregnancy/lactation. This is being implemented in Camden, NJ. Biomarkers of Osteoarthritis: Their Epidemiology
The major goals of this project is to characterize six biomarkers of OA in a population based study to describe the longitudinal initiation and progression of OA over an eight year period and relate that to changes in bone and cartilage markers.
Case Definitions in Osteoarthritis
The major goal of this project is to provide appropriate case definitions of OA based on information from longitudinally taken x-rays, questionnaires about pain, MRI, and BRFS. Depo Provera and Bone Density in Premenopausal Women
The major goals of this project are to describe the longitudinal change in bone mineral density with the administration of depo provera as a contraceptive method. Functional Limitations and the Menopause
The major goals of this project are to characterize measures of physical functioning in a well-characterized cohort of women transitioning the menopause.
SWAN Repository
The major goals of this project is to provide data, serum, urine, DNA Repository from the multi-center SWAN Study. Hormones and Health
The goal is to characterize ovarian hormones and gonadotropins in the MBHS cohort. Estrogen Metabolism and Health Outcomes
The goals are to examine hormone metabolites and receptors in relation to bone, oxidized cholesterol and age a menopause.
Selected Publications
Sowers, M.F., McConnell, D., Jannausch, M., Buyuktur, A.G., Hochberg, M., Jamadar, D.A. (2006). Estradiol and its metabolites and their association with knee osteoarthritis. Arthritis and Rheumatism, 54, 2481-2487.
Sowers M.F., Crawford S., McConnell D.S., Randolph J.F. Jr., Gold E.B., Wilkin M.K., Lasley B. (2006). Selected diet and lifestyle factors are associated with estrogen metabolites in a multi-racial/ethnic population of women. Journal of Nutrition, 136, 1588-95.
Sowers M.F., Jannausch M.L., Gross M., Karvonen-Gutierrez C.A., Palmieri R.M., Crutchfield M., Richards-McCullough K. (2006). Performance-based physical functioning in African-American and Caucasian women at mid-life: Considering body composition, quadriceps strength, and knee osteoarthritis. American Journal of Epidemiology, 163, 950-8.
Sowers M.F., Jannausch M., McConnell D., Little R., Greendale G., Finkelstein J., Neer R., Johnston J., Ettinger B. (April, 2006). Hormone predictors of bone mineral density changes during the menopausal transition: SWAN. Journal of Clinical Endocrinology and Mebolism (Epub ahead of print), 91, 1261-1267.
Hayes C.W., Jamadar D.A., Welch G.W., Jannausch M.L., Lachance L.L., Capul D.C., Sowers M.F. (2005). Osteoarthritis of the knee: Comparison of MR Imaging findings with radiographic severity measurements and pain in middle-aged women. Radiology, 237, 998-1007.
Clark M.K., Dillon J., Sowers M.F., Nichols S. (2005). Weight, fat mass and central distribution of fat increase when women use depot-medroxyprogesterone for contraception. International Journal of Obesity, 29, 1252-1258.
Sowers, M.F., Jannausch M., Randolph J., McConnell D., Little R., Lasley B., Sutton-Tyrrell K., Pasternak R., Matthews K. (2005). Androgens are associated with hemostatic and inflammatory factors among women at the mid-life: SWAN. Journal of Clinical Endocrinology and Metabolism, 90, 6064-6071.
Sowers MF, Crutchfield M, Richards K, Wilkin M, Furniss A, Jannausch M, Zhang D, Gross M. (2005). Sarcopenia is related to physical functioning and leg strength in middle-aged women. The Journals of Gerontology Series A: Bioliological Sciences and Medical Sciences, 60, 486-490.
Clark, K., Sowers, M.F., Nichols, S., Levy, B. (2004). Bone mineral density changes over two years in fist-time users of depot medroxyprogesterone acetate. Fertility & Sterility, 82, 1580-1586.
Randolph, J.F., Sowers, M.F., Bondarenko, I., Harlow, S., Luborsky, J., Little, R. (2004). Change in estradiol and follicle-stimulating hormone across the early menopausal transition: Effects of ethnicity and age. Journal of Clinical Endocrinology Metabolism, 89, 1555-1561.
Professional Affiliations
American Institute of Nutrition
American Public Health Association
American Society for Bone and Mineral Research
American Society for Clinical Nutrition
Endocrine Society
Osteoarthritis Research Society
Society for Epidemiologic Research
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