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Martin Philbert

Martin Philbert, Ph.D.

Dean, School of Public Health

Professor of Toxicology

1822 SPH I      Vcard icon
1415 Washington Heights
Ann Arbor, Michigan 48109-2029

Office: (734) 763-5454; Fax: (734) 763-5455

E-mail: philbert@umich.edu

Professional Summary

Martin Philbert became dean of the University of Michigan School of Public Health on January 1, 2011, having previously served as senior associate dean for research at the school since 2004. He arrived at UM in 1995 from Rutgers' Neurotoxicology Laboratories, where he was a research assistant professor. He has maintained a continuously federally funded portfolio of basic research activities throughout his career. Most recently his work has been funded by the National Institutes of Health, the Department of Air Force and the National Cancer Institute.

At the national level, he is recognized for his expertise in neurotoxicology and experimental neuropathology. He is the author of numerous research publications in top peer-reviewed journals, and one book.

Education

Ph.D., Neurochemistry/Experimental Neuropathology, London University, 1987
B.Sc. (Hons.), Biology/Chemistry, CCAT, Cambridge, 1984

Research Interests & Projects

> > Philbert Lab - Experimental Neurotoxicology and Neuropathology (Leader)

Active research activities include experimental neuropathology, nitrocompound-induced encephalopathies, mitochondrial mechanisms in non-neuronal cell death, development of Nano-Optical Chemical Systems for in vivo physiology, and nanostructure-based imaging and treatment of tumors of malignant gliomas.... More >>

 

> > Jolliet Lab - Impact and Risk Modeling (Member)

The Impact and Risk Modeling (iMod) laboratory aims to provide the scientific knowledge for assessing environmental risks and impacts of chemicals and of innovative technologies, in order to: (1) Model population-based exposure and multi-pathways intake fractions for outdoor and indoor chemical emissions (2) Assess individual and population body burdens and risks using physiologically based pharmacokinetic/dynamic models (3) Assess the life cycle risks, impacts and benefits of new technologies and materials in order to prevent emissions, guide ... More >>

Impact and Risk Modeling 

> > Source to body burden modeling of PAHs and flame retardants toxic impacts (Principal Investigator)

This project aims to explore and better understand the source-to-body fate, exposure and body distribution of polybrominated diphenyl ethers (PBDEs) and PAHs. PBDEs are considered emerging contaminants of great concern due to both their toxicity and the rapidly rising levels found in human and in the environment. The idea is to couple multimedia fate and exposure models with physiologically-based pharmacokinetic (PBPK) models for humans to quantitatively predict variations in body burden as a function of sources, exposure history and personal ... More >>

 

Selected Publications

Search PubMed for publications by Martin Philbert >>

Moser, V.C., Aschner, M., Richardson, R.J., and Philbert, M.A. (2007). Toxic responses of the nervous system In C. Klaassen (Ed.) Casarett and Doull's Toxicology: The Basic Science of Poisons, 7th edition McGraw-Hill, New York.

Gao, D. Xu, H. Philbert, M.A. and Kopelman, R. (2007). Ultrafine hydrogel nanoparticles: synthetic approach and therapeutic application in living cells Angewandte Chemie-International Edition, 13, 2224-7.

Miller, T.J., Schneider, R.J., Miller, J.A., Martin, B.P., Al-Ubaidi, M.R., Agarwal, N., Dethloff, L.A., Philbert, M.A. (2006). Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3. NeuroToxicology, 1, 44-59.

Buck, S.M., Xu, H., Brasuel, M., Philbert, M.A. and Kopelman, R. (2004). Nanoscale probes encapsulated by biologically localized embedding (PEBBLEs) for ion sensing and imaging in live cells. Talanta, In Press.

Leyton, B.E., Sastry, A.M., Wang, H., Sullivan, K.A., Feldman, E.L., Komorowski, T.E. and Philbert, M.A. (2004). Changes in sciatic nerve collagen morphology and distribution in BB rat diabetic neuropathy. J Biomechanics

Koo, Y-E.L., Cao, Y., Kopelman, R., Koo, S.M., Brausuel, M. and Philbert, M.A. (2004). Real-time measurements of dissolved oxygen inside live cells by organically modified silicates fluroescent nanosensors. Anal Chem, 76, 2498-2505.

Park, E., Kopelman, R., Brasuel, M. and Philbert, M.A. (2003). Ratiometric optical PEBBLE nanosensors for magnesium ions in viable cells. Anal Chem, 75, 3784-3791.

Professional Affiliations

2008 - Member and Acting Chair, National Research Council Committee for Review of The Federal Strategy to Address Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials
2007 - Present, Member, Food and Nutrition Board, Institute of Medicine
2007 - Present, Roundtable on Environmental Health Sciences, Research, and Medicine, Institute of Medicine