Professional Summary
2000-present, Associate Professor, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School.
1997-present, Associate Professor, Department of Epidemiology, School of Public Health, University of Michigan.
1996-present, Associate Professor, Genetics Interdepartmental Concentration, School of Public Health, University of Michigan.
2001-present, Director, Glaucoma Research Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School.
1989-1997, Assistant Professor, Department of Epidemiology, School of Public Health, University of Michigan.
1990-1997, Assistant Research Scientist, Department of Ophthalmology, School of Medicine, The University of Michigan.
1993-1997, Senior Associate Research Scientist, Department of Ophthalmology and Visual Sciences School of Medicine, University of Michigan.
Courses Taught
EPID511: Introduction to Public Health Genetics
Syllabus (PDF)
Education
Ph.D., Genetics, University of Wisconsin, 1983
B.S., Microbiology, University of Washington, 1971
Postdoctoral Research Fellow, Department of Human Genetics, University of Michigan, 1990
Postdoctoral Research Fellow, Department of Microbiology and Immunology, University of Michigan, 1986
Postdoctoral Research Fellow, Department of Biological Sciences, Stanford University, 1985
Research Interest & Projects
Molecular Genetics of Glaucoma and Related Disorders.
Expression Profile Approach to Glaucoma Gene Detection.
Genotype Phenotype Studies of Ophthalmic Genetic Disorders.
Development of Software for Integrated Data Management in Genetics Studies.
Selected Publications
Woodroffe, A., Krafchak, C., Richards, J.E., et al. (2006). Ordered Subset Analysis Supports a Glaucoma Locus at GLC1I on chromosome 15 in Families with Earlier Adult Age at Diagnosis Experimental Eye Research, 82, 1068-1074.
Rozsa, F.W., Reed, D.M., Richards, J.E. (2006). Gene expression profile of human trabecular meshwork cells in response to long-term dexamethasone exposure. Molecular Vision, 12, 125-41.
Krafchak, C.M., Pawar, H., Richards, J.E., et al. (2005). Mutations in TCF8 Cause Posterior Polymorphous Corneal Dystrophy and Ectopic Expression of COL4A3 by Corneal Endothelial Cells. American Journal of Human Genetics, 77, 694-708.
Abecasis, G.R., Yashar, B.M., Richards, J.E., et al. (2004). Age-Related Macular Degeneration: A High-Resolution Genome Scan for Susceptibility Loci in a Population Enriched for Late-Stage Disease. American Journal of Human Genetics, 74, 482-494.
Richards, J.E. and Hawley, R.S. (2004). The Human Genome: A Userﾒs Guide Elsevier (San Diego).
Thompson, D.A., McHenry, C.L., Li, Y., Richards, J.E., Othman, M.I., Schwinger, E., Vollrath, D., Jacobson, S.G., Gal, A. (2002). Retinal dystrophy due to paternal isodisomy for chromosome 1 or chromosome 2, with homoallelism for mutations in RPE65 or MERTK, respectively. American Journal of Human Genetics, 70(1), 224-229.
Shimizu, S., Lichter, P.R., Johnson, A.T., Zhou, Z., Higashi, M., Gottfredsdottir, M., Othman, M., Moroi, S.E., Schertzer, R., Clarke, M.S., Schwartz, A.L., Downs, C.A., Vollrath, D., Richards, J.E. (2000). Age-dependent prevalence of mutations at the GLC1A locus in primary open-angle glaucoma. American Journal of Ophthalmology, 130, 165-177.
Rozsa, F., Othman, M.I., Shimizu, S., Lichter, P.R., Johnson, A.T., Scott, K., Nguyen, T.D., Polansky, J.R., Richards, J.E. (1998). GLC1A mutations point to regions of potential functional importance on the TIGR/MYOC protein. Mol Vis, 4:20
Othman, M.I., Sullivan, S.A., Skuta, G.L., Cockrell, D.A., Stringham, H.M., Downs, C.A., Fornes, A., Mick, A., Boehnke, M., Vollrath, D., Richards, J.E. ( 1998). Autosomal dominant nanophthalmos (NNO1) with high hyperopia and angle closure glaucoma maps to chromosome 11. American Journal of Human Genetics, 63, 1411-1418.
Professional Affiliations
Association for Research in Vision and Ophthalmology
American Society of Human Genetics
American Association for the Advancement
Genetics Society of America
Additional Information
Primary appointment and lab are in the Medical School. http://www.kellogg.umich.edu/bios2/richards.research.html. Richards lab Eyegene server: http://eyegene.ophthy.med.umich.edu
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