Professional Summary
Dr. Kardia received her master's degree in statistics and her doctoral degree in human genetics from the University of Michigan. She was then a post-doctoral fellow studying systems biology in the Department of Microbiology and Immunology. She joined the faculty of the University of Michigan School of Public Health in 1998.
Dr. Kardia's main research interests are in the genetic epidemiology of common chronic diseases and their risk factors. She is particularly interested in gene-environment and gene-gene interactions and in developing novel analytical strategies to understand the complex relationship between genetic variation, environmental variation, and risk of common chronic diseases. Her research utilizes genomic, epigenomic, transcriptomic, and proteomic measures on large epidemiological cohorts.
Courses Taught
EPID503: Strategies and Uses of Epidemiology
PUBHLTH510: Intergroup Dialogues on Race, Socio-Economic Status and Health Equity
Education
Ph.D., Human Genetics, University of Michigan, 1991 M.A., Statistics, University of Michigan, 1990
Research Interests & Projects
Dr. Kardia's main research interests are in the genetic epidemiology of cardiovascular disease and its risk factors. She is particularly interested in gene-environment and gene-gene interactions and in developing novel analytical strategies to understand the complex relationship between genetic variation, environmental variation, and risk of common chronic diseases. Dr. Kardia serves with Dr. Toby Citrin as the co-director of both the Life Sciences and Society Program and the Michigan Center for Genomics & Public Health. Dr. Kardia also is the director of the Public Health Genetics Program in the School of Public Health.
Selected Publications
Search PubMed for publications by Sharon Kardia >>
Turner, S.T., Kardia, S.L.R., Boerwinkle, E., deAndrade, M. Multivariate linkage analysis of blood pressure and body mass index General Epidemiology, 27, 64-73.
O'Meara, J., Kardia, S.L.R., Armon, J.J., Turner, S.T. Prevalence, treatment, and control of dyslipidemia in a hypertensive population Archives of Internal Medicine, 164, 1313-1318.
Daniels, P.R., Kardia, S.L.R., Hanis, C.L., Brown, C.A., Hutchinson, R., Boerwinkle, E., Sing, C.F., Turner, S.T. (2004). Familial aggregation of hypertension treatment and control American Journal of Medicine, 116, 676-681.
Sing, C.F., Stengard, J.H., Kardia, S.L.R. (2003). Genes, environment, and cardiovascular disease ATVB, 23, 1190-1196.
Kardia, S.L.R., Modell, S., Peyser, P.A. (2003). Family-centered approaches to understanding and preventing coronary heart disease American Journal of Preventive Medicine, 24, 143-151.
Kardia, S.L.R., Rozek, L.S., Krushkal, J., Ferrell, R.E., Turner, S.T., Hutchinson, R., Brown, A., Sing, C.F., Boerwinkle, E.B. (2003). Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations American Journal Hyt, 16, 154-157.
Small, K.M., Wagoner, L.E., Levin, A.M., Kardia, S.L.R., Liggett, S.B. (2002). Synergistic polymorphisms of ²1- and ±2C-adrenergic receptors and the risk of congestive heart failure New England Journal Medicine, 347, 1135-1142.
Beer, D.G., Kardia, S.L.R., Huang, C.C., Misek, D.E., Lin, L., Chen, G., Gharib, T.G., Giordano, T.J., Thomas, D.G., Lizyness, M.L., Kuick, R, Taylor, J., Iannettoni, M.D., Orringer, M.B., Hanash, S. (2002). Gene-expression profiles predict survival of patients with lung adenocarcinomas Nature Medicine, 8, 816-824.
Schwartz, D.R., Kardia, S.L.R., Shedden, K.A., Kuick, R., Michailidis, G., Taylor, J.M.G., Misek, D.E., Wu, R., Zhai, Y., Darrah, D.M., Reed, H., Ellensen, L.H., Giordano, T.J., Hanash, S.M., Cho, R. (2002). Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas Cancer Research, 62, 4722-4729.
Professional Affiliations
Member, American Heart Association Member, American Public Health Association Member, American Society of Human Genetics Member, American Statistical Association Member, Arteriosclerosis Thrombosis and Vascular Biology Council Member, Atherosclerosis Member, High Blood Pressure Research Council Member, International Biometic Society Member, International Genetic Epidemiology Society Member, Society for Epidemiological Research Member, The American Physiological Society
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