Cathie Spino, Sc.D.

Cathie Spino

Research Associate Professor of Biostatistics

Director of Statistical Analysis of Biomedical and Educational Research (SABER)

M2079 SPH II      Vcard icon
1415 Washington Heights
Ann Arbor, Michigan 48109-2029

Office: (734) 615-5469; Fax: (734) 647-3711


Website(s): Statistical Analysis of Biomedical and Educational Research (SABER)

Curriculum Vitae (PDF)

Professional Summary

Cathie Spino is an Associate Research Professor and Director of Statistical Analysis of Biomedical and Educational Research (SABER) in the Department of Biostatistics.

As the Director of SABER, she collaborates with investigators on the design and analysis of multi-center clinical trials or other research projects, and provides oversight of the infrastructure necessary to conduct these studies, including project management, clinical monitoring, database development and web-based data entry. She joined the department in September 2007, after spending ten years in the pharmaceutical industry as a statistician and statistical manager. She began her career in academia as an assistant professor in the Department of Biostatistics at the Harvard School of Public Health, after receiving her D.Sc. degree there in 1989. She was a statistician in the Statistical and Data Analysis Center (SDAC) of the AIDS Clinical Trials Group (ACTG), and eventually served as the Assistant Director of SDAC for the Pediatric ACTG. Her research interests include clinical trials methodology, particularly adaptive designs, and women's and children's health.

Courses Taught

BIOSTAT558: Clinical Trials and Study Design    Syllabus (PDF)
BIOSTAT599: Planning and Funding Clinical Research    Syllabus (PDF)


Sc.D. , Biostatistics, Harvard University School of Public Health, 1989
M.S., Biostatistics, Harvard University School of Public Health, 1985
B.S., Mathematics and Statistics, Miami University, 1983

Selected Publications

Search PubMed for publications by Cathie Spino >>

Barber, MD, Spino, C, Janz, NK, Brubaker, L, Nygaard, I, Nager, CW and Wheeler, TL for the Pelvic Floor Disorders Network (2009). The Minimum Important Differences for the Urinary Scales of the Pelvic Floor Distress Inventory and Pelvic Floor Impact Questionnaire American Journal of Gynecology, 200:580e1-7. (PMID: 19375574).

Nygaard, I., Barber, M.D., Burgio, K.L., Kenton, K., Meikle, S., Schaffer, J., Spino, C., Whitehead, W.E., Wu, J., Brody, D.J., for the Pelvic Floor Disorders Network (2008). Prevalence of Symptomatic Pelvic Floor Disorders in Women in the United States, 2005-2006 Journal of the American Medical Association, 11, 1311-1316.

Bernstein, H.H., Spino, C., Finch, S., Wasserman, R., Slora, E., Lalama, C., Touloukian, C., Lilienfeld, H., and McCormick, M.C. (2007). Decision-Making for Postpartum Discharge of 4,300 Mothers and Their Healthy Infants: The Life Around Newborn Discharge Study. Pediatrics, Vol. 120 No. 2, 391-400.

Symonds, T., Spino, C., Sisson, M., Soni, P., Martin, M., and Patrick, D. (2007). Methods to Determine the Minimum Important Difference for a Sexual Event Diary Used by Postmenopausal Women with Hypoactive Sexual Desire Disorder. Journal of Sexual Medicine, In Press, 4(5):1328-1355. (PMID: 17727352).

Bird, Shawn J., Brown, Mark J., Spino, C., Watling, S., and Foyt, Howard L. (2006). Value of Repeated Measures of Nerve Conduction and Quantitative Sensory Testing in a Diabetic Neuropathy Trial. Muscle and Nerve, Vol. 34 Iss.2, 214-224.

Currier, J.S., Spino, C., Grimes, J., Wofsy, C.B., Katzenstein, D.A., Hughes, M.D., Hammer, S.M., and Cotton, D.J. (2000). Differences Between Women and Men in Adverse Events and CD4 Responses to Nucleoside Analogue Therapy for HIV Infection. The AIDS Clinical Trials Group 175 Team. Journal of AIDS, Vol. 24 Iss. 4, 316-324.

Watts, D.H., Spino, C., Zaborski, L., Katzenstein, D., Hammer, S., and Benson, C. (1999). Comparison of Gynecologic History and Laboratory Results in HIV-positive Women with CD4+ Lymphocyte Counts between 200 and 500 cells/microl and below 100 cells/microl. Journal of AIDS, Vol. 20 Iss. 5, 455-462.

Spino, C., Kahn, J., Dolin, R., and Phair, J.P. (1997). Predictors of Survival in HIV-infected Persons with 50 or Fewer CD4+ Cells/mm3 Journal of AIDS, Vol. 15 Iss. 5, 346-355.

Baglivo, J., Pagano, M. and Spino, C. (1996). Permutation Distributions via Generating Functions with Applications to Sensitivity Analysis of Discrete Data. Journal of the American Statistical Association, Vol. 91 Iss. 435, 1037- 1046.

Korvick, J.A., Stratton, P., Spino, C., Huang, J., Bardeguez, A., Wolfsy, C. (1996). Women's Participation in AIDS Clinical Trials Group (ACTG) Trials in the USA: Enough or Still Too Few? Journal of Women's Health, Vol. 5 No. 2, 129-136.

Professional Affiliations

American Statistical Association