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Research Groups & Projects for J. Tim Dvonch, Ph.D.
Leader of the following group:
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Dr. Dvonch's work focuses on the exposure assessment, source identification, and health effects of air pollutants. He obtained a B.S. in Chemistry in 1992. In 1994, he earned an M.S. in Environmental Health Sciences, and subsequently a Ph.D. in Environmental Health Sciences in 1998. Dr. Dvonch collaborates on several large multi-disciplinary projects focused on environmental exposures and their related effects on health.... More >> |
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Current Member of the following groups:
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Our research in environmental epidemiology addresses associations between air pollution and health, climate change and health (with a specific emphasis on extreme temperatures) and environmental equity. Most research is accomplished using secondary datasets, including vital statistics data based in the U.S. and Latin America (Mexico, Chile and Brazil); data from large epidemiologic cohorts (Normative Aging Study, Multi-Ethnic Study of Atherosclerosis), data from a study of asthmatic children in Detroit; exposure data derived from ambient temperature and air pollution monitoring ... More >> |
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The Air Quality Laboratory (AQL) presents a unique interdisciplinary approach to solving complex environmental problems, and for investigating fundamental scientific questions and processes. Research interests include the measurement and modeling of hazardous air pollutants (HAPs), air pollution meteorology, whole ecosystem studies of the cycling of trace elements in the environment.... More >> |
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Principal Investigator in the following projects:
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Goal: To develop a PM2.5 extraction protocol suitable for in vitro mechanistic studies; to develop an in vitro assay of PM2.5 effect on respiratory epithelial cells; to determine variation in epithelial cellular responses by PM composition profile using sample filters collected at different geographic locations representing 8 different mixtures of PM2.5 emission sources and investigate interactive effects with rhinovirus.... More >> |
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Goal: To quantify the collocated collection efficiency of the EPA modified SEAS II slurry sampler. To investigate the SEAS II collection efficiency of size segregated aerosols for use in source apportionment studies. ... More >> |
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Co-Principal Investigator in the following projects:
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Goal: To elucidate the underlying patho-physiological mechanisms linking air pollution with impaired arterial reactivity; to clarify the health significance of air pollution-mediated arterial vasoconstriction.... More >> |
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Goal: To provide insight into toxicological mechanisms of PM-induced cardiopulmonary effects, particularly as they relate to susceptible subpopulations; and generate toxicological data to directly correspond to epidemiology and exposure assessment data from concurrent studies being conducted at one of the project locations.... More >> |
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Goal: To conduct a pilot study to demonstrate the feasibility of investigating the effect of concentrated ambient PM2.5 inhalation upon coronary vascular function determined by cardiac positron emission tomography.... More >> |
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Goal: To study the effect of PM2.5 pre-exposure on blood pressure and vascular function following angiotensin II infusion; and to investigate the role of vasoconstrictor mechanisms activated by ROS in response to PM2.5 pre-exposure.... More >> |
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Goal: To demonstrate that short-term concentrated ambient coarse PM (CAP) inhalation (1) triggers pro-vasoconstrictive vascular dysfunctions related to (mediated by) CV autonomic imbalance; and (2) that these responses occur in African American and White adults alike following exposure to both urban and rural coarse PM; and (3) to elucidate the constituents/sources responsible for the CV responses and to perform detailed characterizations of differences in rural vs. urban coarse PM to improve the epidemiological understanding of coarse PM.... More >> |
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Goal: To assess community member's perceptions of the built environment in Detroit, MI and its impact on prevention of cardiovascular disease; to assess community member's perceptions and knowledge about the built environment and impact on physical activity, dietary practices, and obesity; to design and implement a pilot study around potentially modifiable aspects of the built environment to improve community cardiovascular health.... More >> |
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Goal: To quantify the levels of speciated ambient Hg and Hg deposition (wet and dry) at two sites: Chicago, IL and Holland, MI; to investigate the transport, transformation and deposition of Hg from an urban source region to downwind receptor locations across southern Lake Michigan; to determine the spatial and temporal scales for speciated ambient Hg transport and chemistry downwind from an urban area, across southern Lake Michigan.... More >> |
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Goal: To investigate and quantify the sources contributing to atmospheric mercury deposition at four receptor sites in Illinois. ... More >> |
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Goal: To investigate spatial gradients in the deposition of atmospheric mercury across south Florida; and to determine the sources and source locations contributing to the deposited mercury. ... More >> |
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Goal: To address the recommendations to States by USEPA regarding Mercury Reduction Programs, including: 1) identification of the potential air emission sources or source categories contributing to local and regional atmospheric mercury deposition, as well as, 2) the support of long-term atmospheric mercury monitoring networks, in Michigan. ... More >> |
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Goal: To investigate as a primary endpoint if atorvastatin 40 mg/d for 3 weeks is capable of significantly mitigating the vascular endothelial dysfunction due to acute 1-hr exposure to environmental tobacco smoke.... More >> |
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