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Research Groups & Projects for Howard Hu, M.D., M.P.H., Sc.D.
Leader of the following group:
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The Mission of the Michigan Environmental Molecular Epidemiology Research Group (EMERG) is to gain new insights into the impacts of exposure to potentially toxicants that are of critical importance to public health and medicine by applying multi-disciplinary and novel methods of exposure assessment, genetics, epigenetics, nutrition, psychosocial factors and clinical measurements in epidemiologic studies of human populations around the world.... More >> |
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Current Member of the following groups:
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The University of Michigan School of Public Health houses one of the oldest Preventive Medicine Residency programs in the country, dating back to 1969. The central mission of the School of Public Health's residency in General Preventive Medicine and Public Health is to train highly-qualified physicians for careers in public health, clinical preventive medicine, medical epidemiology and health administration.
Our mission is accomplished through the provision of rigorous academic course work resulting in a Master of Public Health degree in general ... More >> |
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We study the transmission of infectious diseases that are mediated through the environment. This includes not only waterborne and vectorborne pathogens, but also other pathogens that survive in the environment such as influenza and MRSA.... More >> |
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Principal Investigator in the following projects:
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The Early Life Exposure in Mexico to ENvironmental Toxicants (ELEMENT) Project is a group of epidemiologic birth cohort studies with the mission of investigating the influence of environmental toxicant exposures on the development and future health of the fetus and infant. ... More >> |
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The Normative Aging Study (NAS) is a longitudinal study of 2,280 healthy male volunteers begun in Boston in the 1960s. Beginning in 1991 with an NIEHS R01 grant to study the impact of environmental lead exposure on risk of hypertension (NIEHS R01 ES 05257; PI: Howard Hu), NAS participants were invited to undergo bone and blood lead measurements. This project and a series of successful competitive renewals produced a number of papers in JAMA, the American Journal of ... More >> |
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Lead exposure poses a major environmental health problem in India. No direct studies have yet been performed in India to investigate the impact of lead exposure on outcomes such as neurobehavioral development. We propose to build upon a collaborative effort initiated during the proposed PI's work as a Senior Fulbright Scholar and work with colleagues at the Sri Ramachandra Medical College and Research Institute of Chennai (formerly known as Madras), Tamil Nadu, India, to study 750 children aged 4-6 attending ... More >> |
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In June of 2004, we established a new Center for Children's Environmental Health and Disease Prevention Research with support from the U.S. Environmental Protection Agency and the National Institute for Environmental Health Sciences. Our Center addresses the concerns of a community living in the Tar Creek Superfund site of Oklahoma - an area highly contaminated by metals (lead, cadmium, iron, manganese, and others) in mining waste and populated by many residents of Native American descent. Our overall goal is to ... More >> |
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Exposure to metals, particularly lead, has been associated with the development of PD in a few but highly-suggestive studies. This topic has not yet been studied epidemiologically using state-of-the-art biological marker techniques for measuring metals exposure and accumulation.
Our research team has taken advantage of well-described, highly motivated and geographically convenient populations of PD patients and potential controls, state-of-the-art methods for measuring biological markers of metals exposure, polymerase chain reaction (PCR) assays, assessment of pesticide exposure, and a highly-experienced team ... More >> |
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This project combines comprehensive lead exposure measurements, APP-pathway gene-specific epigenetic approaches, and genome-wide epigenomic approaches in a novel investigation capitalizing on resources of the MADRC, the Michigan Claude D. Pepper Geriatrics Center, and the National Alzheimer’s Coordinating Center (NACC).... More >> |
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Co-Principal Investigator in the following project:
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The University of Michigan Center for Occupational Health and Safety Engineering (COHSE), a NIOSH-funded Education and Research Center (ERC), provides comprehensive professional and research training in Industrial Hygiene (IH), Occupational Health Nursing (OHN), Occupational Safety Engineering and Ergonomics (OSE), Hazardous Substances Academic Training (HSAT), Occupational Epidemiology (OE), and Pilot Project Research Training (PPRT). We have functioned as an ERC since 1982. The ERC provide direct funding of Masters and doctoral students, as well as pilot research projects, and generally ... More >> |
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Co-Investigator in the following project:
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The goal of this project is to establish job-exposure matrix to estimate occupational noise exposure using O*NET databases, and to test the hypothesis of joint adverse effects of noise and lead on age-related hearing loss among older adults.... More >> |
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Additional Personnel in the following project:
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The major goals of this project are to understand how long-term environmental exposures to lead and air pollution affect age-related pathological changes, namely, depressed cardiac function, age-related cataract and hearing loss, and to identify genetic and nutritional factors that impact susceptibility to such pollutants in an aging population.... More >> |
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