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Kardia Lab - Genetic Epidemiology

Courses

EPID503 Strategies and Uses of Epidemiology
Winter term(s)
3 Credit Hour(s)
Instructor(s): Kardia, Sharon; Adar, Sara; Lisabeth, Lynda; Tomey, KT
Offered every year
Last offered Winter 2013
Prerequisites: Biostat 503, Grad Status
Description: This course offers an introduction to the principles, concepts, and methods of population-based epidemiologic research. It is intended to be the introductory course for students who are NOT majoring in Epidemiology. The course will be divided into three primary sections. The first section will serve as an introduction to the basic principles of epidemiology and the measures used in epidemiology. The second section will discuss epidemiologic study design (including case-control, cohort studies) and analysis (including bias, confounding, effect modification). The third section will cover special topics that are important to an introductory understanding of epidemiology (including outbreak investigations, screening, and the role of epidemiology in public health.

EPID513 Applications in Public Health Genetics
Fall term(s)
1 Credit Hour(s)
Instructor(s): Kardia, Sharon
Last offered Fall 2006
Not offered 2012-2013
Description: A forum for discussing applications of public health genetics and for integrating recent developments in human genetics into the breadth of public health genetics. Topics will be inclusive, from genetics and molecular biology, to assessment, policy development, screening for genetic susceptibility, and ethical, legal, and social issues as they apply to delivery of public health genetics.

EPID817 Advanced Genomic Epidemiology
Winter term(s)
3 Credit Hour(s)
Instructor(s): Kardia, Sharon
Not offered 2012-2013
Prerequisites: BIOSTAT 560 EPID 515 or equivalent
Description: This course provides a depth of experience in advanced genomic epidemiology methods. The focus will be on developing and implementing high throughput analyses of single nucleotide polymorphisms and their association with disease. Analytical methods such as linkage disequilibrium testing, haplotype estimation, gene-environment interactions, gene-gene interactions, classification trees, and neural networks will be reviewed and then applied to a real dataset. We will also review and apply the many bioinformatic resources available from the National Center for Biotechnology and Information (NCBI) to provide a biological context to the analysis and facilitate interpretation of genomic epidemiological association studies. Emphasis will also be placed on issues of statistical hypothesis testing such as the multiple testing (e.g. adjusting p-values using false discovery rate methods and permutation methods) and will learn techniques for performing cross-validation. Students will get hands on experience with creating analysis plans, performing data analysis, and interpreting genomic association results.

PUBHLTH510 Intergroup Dialogues on Race, Socio-Economic Status and Health Equity
Fall term(s)
2 Credit Hour(s)
Instructor(s): Kardia, Sharon
Prerequisites: None
Description: Issues of health equity are often correlated with social/cultural aspects of communities and their differential access to power, privilege, and health resources. In this intergroup dialogue, students will participate in semi-structured face-to-face meetings across racial and socio-economic status to better understand their personal and professional roles in reducing health inequity.
Course Goals: Our long-term goal is to achieve a sustainable shift in the personal and collective skill set of our students to begin to address some of society's toughest issues such as racism, poverty, hatred, and other social injustices. Each of these social elements has a direct impact on people's health and longevity. Societal solutions to social injustices will not arise solely through the accumulation of new data but will need to be accompanied by the acquisition of new skills, including deep interpersonal engagement and advocacy for creative solutions.
Competencies: Competencies (ASPH Competency): Diversity and Culture • Describe the roles of, history, power, privilege and structural inequality in producing health disparities. (G.1.) • Explain why cultural competence alone cannot address health disparity. (G.3.) • Use the basic concepts and skills involved in culturally appropriate community engagement and empowerment with diverse communities. (G.5.) • Cite examples of situations where consideration of culture-specific needs resulted in a more effective modification or adaptation of a health intervention. (G.9.) • Develop public health programs and strategies responsive to the diverse cultural values and traditions of the communities being served. (G.10.) Leadership • Engage in dialogue and learning from others to advance public health goals. (H.4.) • Demonstrate team building, negotiation, and conflict management skills. (H.5.) • Demonstrate transparency, integrity, and honesty in all actions. (H.6.) • Apply social justice and human rights principles when addressing community needs. (H.8.) Professionalism • Promote high standards of personal and organizational integrity, compassion, honesty and respect for all people. (J.5.) • Embrace a definition of public health that captures the unique characteristics of the field (e.g., population-focused, community-oriented, prevention-motivated and rooted in social justice) and how these contribute to professional practice. (J.9.)