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RESEARCH
- Drug-resistant malaria Malaria
affects hundreds of millions of people in the developing
world, killing 2 million children each year. Malaria
strains have become resistant to most of the available
drugs. We are attempting to understand how drug
resistance develops through mathematical modelling and
molecular epidemiology.
- Malaria in pregnancy
Malaria has a profound effect on pregnant women and
is a frequent cause of the delivery low-birth weight
infants. It also interacts with HIV in ways not yet fully
understood. We are attempting to determine the mechanisms
by which malaria affects the fetus and by which it may
affect the vertical transmission of HIV.
- Pneumocystis carinii pneumonia
(PCP), is the most common severe opportunistic infection
in people with AIDS. We were the first to present
evidence that this organism is becoming drug-resistant,
and are following up these observations with both
molecular biological and epidemiological studies.
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